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Page 1
Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic functioning.
Neumann A, Ohlei O, Küçükali F, Bos IJ, Timsina J, Vos S, Prokopenko D, Tijms BM, Andreasson U, Blennow K, Vandenberghe R, Scheltens P, Teunissen CE, Engelborghs S, Frisoni GB, Blin O, Richardson JC, Bordet R, Lleó A, Alcolea D, Popp J, Marsh TW, Gorijala P, Clark C, Peyratout G, Martinez-Lage P, Tainta M, Dobson RJB, Legido-Quigley C, Van Broeckhoven C, Tanzi RE, Ten Kate M, Lill CM, Barkhof F, Cruchaga C, Lovestone S, Streffer J, Zetterberg H, Visser PJ, Sleegers K, Bertram L; EMIF-AD & ADNI study group. Neumann A, et al. Among authors: timsina j. Genome Med. 2023 Oct 4;15(1):79. doi: 10.1186/s13073-023-01233-z. Genome Med. 2023. PMID: 37794492 Free PMC article.
Comparative Analysis of Alzheimer's Disease Cerebrospinal Fluid Biomarkers Measurement by Multiplex SOMAscan Platform and Immunoassay-Based Approach.
Timsina J, Gomez-Fonseca D, Wang L, Do A, Western D, Alvarez I, Aguilar M, Pastor P, Henson RL, Herries E, Xiong C, Schindler SE, Fagan AM, Bateman RJ, Farlow M, Morris JC, Perrin RJ, Moulder K, Hassenstab J, Vöglein J, Chhatwal J, Mori H; Alzheimer’s Disease Neuroimaging Initiative; Dominantly Inherited Alzheimer Network Consortia; Sung YJ, Cruchaga C. Timsina J, et al. J Alzheimers Dis. 2022;89(1):193-207. doi: 10.3233/JAD-220399. J Alzheimers Dis. 2022. PMID: 35871346 Free PMC article.
Plasma proteomics of SARS-CoV-2 infection and severity reveals impact on Alzheimer's and coronary disease pathways.
Wang L, Western D, Timsina J, Repaci C, Song WM, Norton J, Kohlfeld P, Budde J, Climer S, Butt OH, Jacobson D, Garvin M, Templeton AR, Campagna S, O'Halloran J, Presti R, Goss CW, Mudd PA, Ances BM, Zhang B, Sung YJ, Cruchaga C. Wang L, et al. Among authors: timsina j. iScience. 2023 Apr 21;26(4):106408. doi: 10.1016/j.isci.2023.106408. Epub 2023 Mar 14. iScience. 2023. PMID: 36974157 Free PMC article.
Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease.
Ali M, Archer DB, Gorijala P, Western D, Timsina J, Fernández MV, Wang TC, Satizabal CL, Yang Q, Beiser AS, Wang R, Chen G, Gordon B, Benzinger TLS, Xiong C, Morris JC, Bateman RJ, Karch CM, McDade E, Goate A, Seshadri S, Mayeux RP, Sperling RA, Buckley RF, Johnson KA, Won HH, Jung SH, Kim HR, Seo SW, Kim HJ, Mormino E, Laws SM, Fan KH, Kamboh MI, Vemuri P, Ramanan VK, Yang HS, Wenzel A, Rajula HSR, Mishra A, Dufouil C, Debette S, Lopez OL, DeKosky ST, Tao F, Nagle MW; Knight Alzheimer Disease Research Center (Knight ADRC); Dominantly Inherited Alzheimer Network (DIAN); Alzheimer’s Disease Neuroimaging Initiative (ADNI); ADNI-DOD, A4 Study Team; Australian Imaging Biomarkers, Lifestyle (AIBL) Study; Hohman TJ, Sung YJ, Dumitrescu L, Cruchaga C. Ali M, et al. Among authors: timsina j. Acta Neuropathol Commun. 2023 Apr 26;11(1):68. doi: 10.1186/s40478-023-01563-4. Acta Neuropathol Commun. 2023. PMID: 37101235 Free PMC article.
Proteome wide association studies of LRRK2 variants identify novel causal and druggable proteins for Parkinson's disease.
Phillips B, Western D, Wang L, Timsina J, Sun Y, Gorijala P, Yang C, Do A, Nykänen NP, Alvarez I, Aguilar M, Pastor P, Morris JC, Schindler SE, Fagan AM, Puerta R, García-González P, de Rojas I, Marquié M, Boada M, Ruiz A, Perlmutter JS; Dominantly Inherited Alzheimer Network (DIAN) Consortia; Ibanez L, Perrin RJ, Sung YJ, Cruchaga C. Phillips B, et al. Among authors: timsina j. NPJ Parkinsons Dis. 2023 Jul 8;9(1):107. doi: 10.1038/s41531-023-00555-4. NPJ Parkinsons Dis. 2023. PMID: 37422510 Free PMC article.
Organ aging signatures in the plasma proteome track health and disease.
Oh HS, Rutledge J, Nachun D, Pálovics R, Abiose O, Moran-Losada P, Channappa D, Urey DY, Kim K, Sung YJ, Wang L, Timsina J, Western D, Liu M, Kohlfeld P, Budde J, Wilson EN, Guen Y, Maurer TM, Haney M, Yang AC, He Z, Greicius MD, Andreasson KI, Sathyan S, Weiss EF, Milman S, Barzilai N, Cruchaga C, Wagner AD, Mormino E, Lehallier B, Henderson VW, Longo FM, Montgomery SB, Wyss-Coray T. Oh HS, et al. Among authors: timsina j. Nature. 2023 Dec;624(7990):164-172. doi: 10.1038/s41586-023-06802-1. Epub 2023 Dec 6. Nature. 2023. PMID: 38057571 Free PMC article.
Blood-Based Proteomics for Adult-Onset Focal Dystonias.
Timsina J, Dinasarapu A, Kilic-Berkmen G, Budde J, Sung YJ, Klein AM, Cruchaga C, Jinnah HA. Timsina J, et al. Ann Neurol. 2024 Apr 5. doi: 10.1002/ana.26929. Online ahead of print. Ann Neurol. 2024. PMID: 38578115
CSF biomarkers of immune activation and Alzheimer's disease for predicting cognitive impairment risk in the elderly.
Shue F, White LJ, Hendrix R, Ulrich J, Henson RL, Knight W, Martens YA, Wang N, Roy B, Starling SC, Ren Y, Xiong C, Asmann YW, Syrjanen JA, Vassilaki M, Mielke MM, Timsina J, Sung YJ, Cruchaga C, Holtzman DM, Bu G, Petersen RC, Heckman MG, Kanekiyo T. Shue F, et al. Among authors: timsina j. Sci Adv. 2024 Apr 5;10(14):eadk3674. doi: 10.1126/sciadv.adk3674. Epub 2024 Apr 3. Sci Adv. 2024. PMID: 38569027 Free PMC article.
CSF proteomic profiling with amyloid/tau positivity identifies distinctive sex-different alteration of multiple proteins involved in Alzheimer's disease.
Do AN, Ali M, Timsina J, Wang L, Western D, Liu M, Sanford J, Rosende-Roca M, Boada M, Puerta R, Wilson T, Ruiz A, Pastor P; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Wyss-Coray T, Cruchaga C, Sung YJ. Do AN, et al. Among authors: timsina j. medRxiv [Preprint]. 2024 Mar 16:2024.03.15.24304164. doi: 10.1101/2024.03.15.24304164. medRxiv. 2024. PMID: 38559166 Free PMC article. Preprint.
31 results