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Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype.
Valdés-Mora F, Salomon R, Gloss BS, Law AMK, Venhuizen J, Castillo L, Murphy KJ, Magenau A, Papanicolaou M, Rodriguez de la Fuente L, Roden DL, Colino-Sanguino Y, Kikhtyak Z, Farbehi N, Conway JRW, Sikta N, Oakes SR, Cox TR, O'Donoghue SI, Timpson P, Ormandy CJ, Gallego-Ortega D. Valdés-Mora F, et al. Among authors: timpson p. Cell Rep. 2021 Apr 13;35(2):108945. doi: 10.1016/j.celrep.2021.108945. Cell Rep. 2021. PMID: 33852842 Free article.
The Rac-FRET mouse reveals tight spatiotemporal control of Rac activity in primary cells and tissues.
Johnsson AE, Dai Y, Nobis M, Baker MJ, McGhee EJ, Walker S, Schwarz JP, Kadir S, Morton JP, Myant KB, Huels DJ, Segonds-Pichon A, Sansom OJ, Anderson KI, Timpson P, Welch HCE. Johnsson AE, et al. Among authors: timpson p. Cell Rep. 2014 Mar 27;6(6):1153-1164. doi: 10.1016/j.celrep.2014.02.024. Epub 2014 Mar 13. Cell Rep. 2014. PMID: 24630994 Free PMC article.
Cholesterol regulates Syntaxin 6 trafficking at trans-Golgi network endosomal boundaries.
Reverter M, Rentero C, Garcia-Melero A, Hoque M, Vilà de Muga S, Alvarez-Guaita A, Conway JR, Wood P, Cairns R, Lykopoulou L, Grinberg D, Vilageliu L, Bosch M, Heeren J, Blasi J, Timpson P, Pol A, Tebar F, Murray RZ, Grewal T, Enrich C. Reverter M, et al. Among authors: timpson p. Cell Rep. 2014 May 8;7(3):883-97. doi: 10.1016/j.celrep.2014.03.043. Epub 2014 Apr 17. Cell Rep. 2014. PMID: 24746815 Free article.
A Negative Regulatory Mechanism Involving 14-3-3ζ Limits Signaling Downstream of ROCK to Regulate Tissue Stiffness in Epidermal Homeostasis.
Kular J, Scheer KG, Pyne NT, Allam AH, Pollard AN, Magenau A, Wright RL, Kolesnikoff N, Moretti PA, Wullkopf L, Stomski FC, Cowin AJ, Woodcock JM, Grimbaldeston MA, Pitson SM, Timpson P, Ramshaw HS, Lopez AF, Samuel MS. Kular J, et al. Among authors: timpson p. Dev Cell. 2015 Dec 21;35(6):759-74. doi: 10.1016/j.devcel.2015.11.026. Dev Cell. 2015. PMID: 26702834 Free article.
ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells.
Gallego-Ortega D, Ledger A, Roden DL, Law AM, Magenau A, Kikhtyak Z, Cho C, Allerdice SL, Lee HJ, Valdes-Mora F, Herrmann D, Salomon R, Young AI, Lee BY, Sergio CM, Kaplan W, Piggin C, Conway JR, Rabinovich B, Millar EK, Oakes SR, Chtanova T, Swarbrick A, Naylor MJ, O'Toole S, Green AR, Timpson P, Gee JM, Ellis IO, Clark SJ, Ormandy CJ. Gallego-Ortega D, et al. Among authors: timpson p. PLoS Biol. 2015 Dec 30;13(12):e1002330. doi: 10.1371/journal.pbio.1002330. eCollection 2015 Dec. PLoS Biol. 2015. PMID: 26717410 Free PMC article.
144 results