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Stromal cell diversity associated with immune evasion in human triple-negative breast cancer.
Wu SZ, Roden DL, Wang C, Holliday H, Harvey K, Cazet AS, Murphy KJ, Pereira B, Al-Eryani G, Bartonicek N, Hou R, Torpy JR, Junankar S, Chan CL, Lam CE, Hui MN, Gluch L, Beith J, Parker A, Robbins E, Segara D, Mak C, Cooper C, Warrier S, Forrest A, Powell J, O'Toole S, Cox TR, Timpson P, Lim E, Liu XS, Swarbrick A. Wu SZ, et al. Among authors: timpson p. EMBO J. 2020 Oct 1;39(19):e104063. doi: 10.15252/embj.2019104063. Epub 2020 Aug 13. EMBO J. 2020. PMID: 32790115 Free PMC article.
ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells.
Gallego-Ortega D, Ledger A, Roden DL, Law AM, Magenau A, Kikhtyak Z, Cho C, Allerdice SL, Lee HJ, Valdes-Mora F, Herrmann D, Salomon R, Young AI, Lee BY, Sergio CM, Kaplan W, Piggin C, Conway JR, Rabinovich B, Millar EK, Oakes SR, Chtanova T, Swarbrick A, Naylor MJ, O'Toole S, Green AR, Timpson P, Gee JM, Ellis IO, Clark SJ, Ormandy CJ. Gallego-Ortega D, et al. Among authors: timpson p. PLoS Biol. 2015 Dec 30;13(12):e1002330. doi: 10.1371/journal.pbio.1002330. eCollection 2015 Dec. PLoS Biol. 2015. PMID: 26717410 Free PMC article.
MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib.
Young AI, Law AM, Castillo L, Chong S, Cullen HD, Koehler M, Herzog S, Brummer T, Lee EF, Fairlie WD, Lucas MC, Herrmann D, Allam A, Timpson P, Watkins DN, Millar EK, O'Toole SA, Gallego-Ortega D, Ormandy CJ, Oakes SR. Young AI, et al. Among authors: timpson p. Breast Cancer Res. 2016 Dec 8;18(1):125. doi: 10.1186/s13058-016-0781-6. Breast Cancer Res. 2016. PMID: 27931239 Free PMC article.
Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer.
Chang J, Lucas MC, Leonte LE, Garcia-Montolio M, Singh LB, Findlay AD, Deodhar M, Foot JS, Jarolimek W, Timpson P, Erler JT, Cox TR. Chang J, et al. Among authors: timpson p. Oncotarget. 2017 Apr 18;8(16):26066-26078. doi: 10.18632/oncotarget.15257. Oncotarget. 2017. PMID: 28199967 Free PMC article.
Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer.
Chou A, Froio D, Nagrial AM, Parkin A, Murphy KJ, Chin VT, Wohl D, Steinmann A, Stark R, Drury A, Walters SN, Vennin C, Burgess A, Pinese M, Chantrill LA, Cowley MJ, Molloy TJ; Australian Pancreatic Cancer Genome Initiative (APGI); Waddell N, Johns A, Grimmond SM, Chang DK, Biankin AV, Sansom OJ, Morton JP, Grey ST, Cox TR, Turchini J, Samra J, Clarke SJ, Timpson P, Gill AJ, Pajic M. Chou A, et al. Among authors: timpson p. Gut. 2018 Dec;67(12):2142-2155. doi: 10.1136/gutjnl-2017-315144. Epub 2017 Oct 28. Gut. 2018. PMID: 29080858 Free PMC article.
Reshaping the Tumor Stroma for Treatment of Pancreatic Cancer.
Vennin C, Murphy KJ, Morton JP, Cox TR, Pajic M, Timpson P. Vennin C, et al. Among authors: timpson p. Gastroenterology. 2018 Mar;154(4):820-838. doi: 10.1053/j.gastro.2017.11.280. Epub 2017 Dec 26. Gastroenterology. 2018. PMID: 29287624 Review.
144 results