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Structural and kinetic determinants of protease substrates.
Timmer JC, Zhu W, Pop C, Regan T, Snipas SJ, Eroshkin AM, Riedl SJ, Salvesen GS. Timmer JC, et al. Nat Struct Mol Biol. 2009 Oct;16(10):1101-8. doi: 10.1038/nsmb.1668. Epub 2009 Sep 20. Nat Struct Mol Biol. 2009. PMID: 19767749 Free PMC article.
The apoptosome activates caspase-9 by dimerization.
Pop C, Timmer J, Sperandio S, Salvesen GS. Pop C, et al. Mol Cell. 2006 Apr 21;22(2):269-75. doi: 10.1016/j.molcel.2006.03.009. Mol Cell. 2006. PMID: 16630894 Free article.
Caspase substrates.
Timmer JC, Salvesen GS. Timmer JC, et al. Cell Death Differ. 2007 Jan;14(1):66-72. doi: 10.1038/sj.cdd.4402059. Epub 2006 Nov 3. Cell Death Differ. 2007. PMID: 17082814 Review.
Profiling constitutive proteolytic events in vivo.
Timmer JC, Enoksson M, Wildfang E, Zhu W, Igarashi Y, Denault JB, Ma Y, Dummitt B, Chang YH, Mast AE, Eroshkin A, Smith JW, Tao WA, Salvesen GS. Timmer JC, et al. Biochem J. 2007 Oct 1;407(1):41-8. doi: 10.1042/BJ20070775. Biochem J. 2007. PMID: 17650073 Free PMC article.
Modulation of CD47-SIRPα innate immune checkpoint axis with Fc-function detuned anti-CD47 therapeutic antibody.
Narla RK, Modi H, Bauer D, Abbasian M, Leisten J, Piccotti JR, Kopytek S, Eckelman BP, Deveraux Q, Timmer J, Zhu D, Wong L, Escoubet L, Raymon HK, Hariharan K. Narla RK, et al. Cancer Immunol Immunother. 2022 Feb;71(2):473-489. doi: 10.1007/s00262-021-03010-6. Epub 2021 Jul 10. Cancer Immunol Immunother. 2022. PMID: 34247273 Free PMC article.
16 results