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New diterpenes from the marine sponge Spongionella sp. overcome drug resistance in prostate cancer by inhibition of P-glycoprotein.
Dyshlovoy SA, Shubina LK, Makarieva TN, Hauschild J, Strewinsky N, Guzii AG, Menshov AS, Popov RS, Grebnev BB, Busenbender T, Oh-Hohenhorst SJ, Maurer T, Tilki D, Graefen M, Bokemeyer C, Stonik VA, von Amsberg G. Dyshlovoy SA, et al. Among authors: tilki d. Sci Rep. 2022 Aug 9;12(1):13570. doi: 10.1038/s41598-022-17447-x. Sci Rep. 2022. PMID: 35945234 Free PMC article.
Additional androgen deprivation makes the difference: Biochemical recurrence-free survival in prostate cancer patients after HDR brachytherapy and external beam radiotherapy.
Schiffmann J, Lesmana H, Tennstedt P, Beyer B, Boehm K, Platz V, Tilki D, Salomon G, Petersen C, Krüll A, Graefen M, Schwarz R. Schiffmann J, et al. Among authors: tilki d. Strahlenther Onkol. 2015 Apr;191(4):330-7. doi: 10.1007/s00066-014-0794-y. Epub 2014 Dec 4. Strahlenther Onkol. 2015. PMID: 25471276 Clinical Trial.
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