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Short-term molecular consequences of chromosome mis-segregation for genome stability.
Garribba L, De Feudis G, Martis V, Galli M, Dumont M, Eliezer Y, Wardenaar R, Ippolito MR, Iyer DR, Tijhuis AE, Spierings DCJ, Schubert M, Taglietti S, Soriani C, Gemble S, Basto R, Rhind N, Foijer F, Ben-David U, Fachinetti D, Doksani Y, Santaguida S. Garribba L, et al. Among authors: tijhuis ae. Nat Commun. 2023 Mar 11;14(1):1353. doi: 10.1038/s41467-023-37095-7. Nat Commun. 2023. PMID: 36906648 Free PMC article.
Transient genomic instability drives tumorigenesis through accelerated clonal evolution.
Shoshani O, Bakker B, de Haan L, Tijhuis AE, Wang Y, Kim DH, Maldonado M, Demarest MA, Artates J, Zhengyu O, Mark A, Wardenaar R, Sasik R, Spierings DCJ, Vitre B, Fisch K, Foijer F, Cleveland DW. Shoshani O, et al. Among authors: tijhuis ae. Genes Dev. 2021 Aug 1;35(15-16):1093-1108. doi: 10.1101/gad.348319.121. Epub 2021 Jul 15. Genes Dev. 2021. PMID: 34266887 Free PMC article.
Genetic instability from a single S phase after whole-genome duplication.
Gemble S, Wardenaar R, Keuper K, Srivastava N, Nano M, Macé AS, Tijhuis AE, Bernhard SV, Spierings DCJ, Simon A, Goundiam O, Hochegger H, Piel M, Foijer F, Storchová Z, Basto R. Gemble S, et al. Among authors: tijhuis ae. Nature. 2022 Apr;604(7904):146-151. doi: 10.1038/s41586-022-04578-4. Epub 2022 Mar 30. Nature. 2022. PMID: 35355016 Free PMC article.
cGAS-STING drives the IL-6-dependent survival of chromosomally instable cancers.
Hong C, Schubert M, Tijhuis AE, Requesens M, Roorda M, van den Brink A, Ruiz LA, Bakker PL, van der Sluis T, Pieters W, Chen M, Wardenaar R, van der Vegt B, Spierings DCJ, de Bruyn M, van Vugt MATM, Foijer F. Hong C, et al. Among authors: tijhuis ae. Nature. 2022 Jul;607(7918):366-373. doi: 10.1038/s41586-022-04847-2. Epub 2022 Jun 15. Nature. 2022. PMID: 35705809
Author Correction: Genetic instability from a single S phase after whole-genome duplication.
Gemble S, Wardenaar R, Keuper K, Srivastava N, Nano M, Macé AS, Tijhuis AE, Bernhard SV, Spierings DCJ, Simon A, Goundiam O, Hochegger H, Piel M, Foijer F, Storchová Z, Basto R. Gemble S, et al. Among authors: tijhuis ae. Nature. 2022 Aug;608(7923):E27. doi: 10.1038/s41586-022-05099-w. Nature. 2022. PMID: 35864235 Free PMC article. No abstract available.
Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition.
Gliech CR, Yeow ZY, Tapias-Gomez D, Yang Y, Huang Z, Tijhuis AE, Spierings DC, Foijer F, Chung G, Tamayo N, Bahrami-Nejad Z, Collins P, Nguyen TT, Plata Stapper A, Hughes PE, Payton M, Holland AJ. Gliech CR, et al. Among authors: tijhuis ae. EMBO J. 2024 Mar;43(5):666-694. doi: 10.1038/s44318-024-00031-6. Epub 2024 Jan 26. EMBO J. 2024. PMID: 38279026 Free PMC article.
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