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Stem Cells for Next Level Toxicity Testing in the 21st Century.
Fritsche E, Haarmann-Stemmann T, Kapr J, Galanjuk S, Hartmann J, Mertens PR, Kämpfer AAM, Schins RPF, Tigges J, Koch K. Fritsche E, et al. Among authors: tigges j. Small. 2021 Apr;17(15):e2006252. doi: 10.1002/smll.202006252. Epub 2020 Dec 23. Small. 2021. PMID: 33354870 Review.
Xenobiotic metabolism capacities of human skin in comparison with a 3D epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: activating enzymes (Phase I).
Götz C, Pfeiffer R, Tigges J, Blatz V, Jäckh C, Freytag EM, Fabian E, Landsiedel R, Merk HF, Krutmann J, Edwards RJ, Pease C, Goebel C, Hewitt N, Fritsche E. Götz C, et al. Among authors: tigges j. Exp Dermatol. 2012 May;21(5):358-63. doi: 10.1111/j.1600-0625.2012.01486.x. Exp Dermatol. 2012. PMID: 22509833
Xenobiotic metabolism capacities of human skin in comparison with a 3D-epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: phase II enzymes.
Götz C, Pfeiffer R, Tigges J, Ruwiedel K, Hübenthal U, Merk HF, Krutmann J, Edwards RJ, Abel J, Pease C, Goebel C, Hewitt N, Fritsche E. Götz C, et al. Among authors: tigges j. Exp Dermatol. 2012 May;21(5):364-9. doi: 10.1111/j.1600-0625.2012.01478.x. Exp Dermatol. 2012. PMID: 22509834
Evidence for a novel anti-apoptotic pathway in human keratinocytes involving the aryl hydrocarbon receptor, E2F1, and checkpoint kinase 1.
Frauenstein K, Sydlik U, Tigges J, Majora M, Wiek C, Hanenberg H, Abel J, Esser C, Fritsche E, Krutmann J, Haarmann-Stemmann T. Frauenstein K, et al. Among authors: tigges j. Cell Death Differ. 2013 Oct;20(10):1425-34. doi: 10.1038/cdd.2013.102. Epub 2013 Aug 2. Cell Death Differ. 2013. PMID: 23912710 Free PMC article.
The new aryl hydrocarbon receptor antagonist E/Z-2-benzylindene-5,6-dimethoxy-3,3-dimethylindan-1-one protects against UVB-induced signal transduction.
Tigges J, Haarmann-Stemmann T, Vogel CFA, Grindel A, Hübenthal U, Brenden H, Grether-Beck S, Vielhaber G, Johncock W, Krutmann J, Fritsche E. Tigges J, et al. J Invest Dermatol. 2014 Feb;134(2):556-559. doi: 10.1038/jid.2013.362. Epub 2013 Aug 30. J Invest Dermatol. 2014. PMID: 23995519 Free PMC article. No abstract available.
The hallmarks of fibroblast ageing.
Tigges J, Krutmann J, Fritsche E, Haendeler J, Schaal H, Fischer JW, Kalfalah F, Reinke H, Reifenberger G, Stühler K, Ventura N, Gundermann S, Boukamp P, Boege F. Tigges J, et al. Mech Ageing Dev. 2014 Jun;138:26-44. doi: 10.1016/j.mad.2014.03.004. Epub 2014 Mar 29. Mech Ageing Dev. 2014. PMID: 24686308 Review.
158 results