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Fibroblast origin shapes tissue homeostasis, epidermal differentiation, and drug uptake.
Hausmann C, Zoschke C, Wolff C, Darvin ME, Sochorová M, Kováčik A, Wanjiku B, Schumacher F, Tigges J, Kleuser B, Lademann J, Fritsche E, Vávrová K, Ma N, Schäfer-Korting M. Hausmann C, et al. Among authors: tigges j. Sci Rep. 2019 Feb 27;9(1):2913. doi: 10.1038/s41598-019-39770-6. Sci Rep. 2019. PMID: 30814627 Free PMC article.
Xenobiotic metabolism capacities of human skin in comparison with a 3D epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: activating enzymes (Phase I).
Götz C, Pfeiffer R, Tigges J, Blatz V, Jäckh C, Freytag EM, Fabian E, Landsiedel R, Merk HF, Krutmann J, Edwards RJ, Pease C, Goebel C, Hewitt N, Fritsche E. Götz C, et al. Among authors: tigges j. Exp Dermatol. 2012 May;21(5):358-63. doi: 10.1111/j.1600-0625.2012.01486.x. Exp Dermatol. 2012. PMID: 22509833
Xenobiotic metabolism capacities of human skin in comparison with a 3D-epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: phase II enzymes.
Götz C, Pfeiffer R, Tigges J, Ruwiedel K, Hübenthal U, Merk HF, Krutmann J, Edwards RJ, Abel J, Pease C, Goebel C, Hewitt N, Fritsche E. Götz C, et al. Among authors: tigges j. Exp Dermatol. 2012 May;21(5):364-9. doi: 10.1111/j.1600-0625.2012.01478.x. Exp Dermatol. 2012. PMID: 22509834
Evidence for a novel anti-apoptotic pathway in human keratinocytes involving the aryl hydrocarbon receptor, E2F1, and checkpoint kinase 1.
Frauenstein K, Sydlik U, Tigges J, Majora M, Wiek C, Hanenberg H, Abel J, Esser C, Fritsche E, Krutmann J, Haarmann-Stemmann T. Frauenstein K, et al. Among authors: tigges j. Cell Death Differ. 2013 Oct;20(10):1425-34. doi: 10.1038/cdd.2013.102. Epub 2013 Aug 2. Cell Death Differ. 2013. PMID: 23912710 Free PMC article.
The hallmarks of fibroblast ageing.
Tigges J, Krutmann J, Fritsche E, Haendeler J, Schaal H, Fischer JW, Kalfalah F, Reinke H, Reifenberger G, Stühler K, Ventura N, Gundermann S, Boukamp P, Boege F. Tigges J, et al. Mech Ageing Dev. 2014 Jun;138:26-44. doi: 10.1016/j.mad.2014.03.004. Epub 2014 Mar 29. Mech Ageing Dev. 2014. PMID: 24686308 Review.
Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2).
Frauenstein K, Tigges J, Soshilov AA, Kado S, Raab N, Fritsche E, Haendeler J, Denison MS, Vogel CF, Haarmann-Stemmann T. Frauenstein K, et al. Among authors: tigges j. Arch Toxicol. 2015 Aug;89(8):1329-36. doi: 10.1007/s00204-014-1321-8. Epub 2014 Aug 1. Arch Toxicol. 2015. PMID: 25082669 Free PMC article.
158 results