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Inducing trained immunity in pro-metastatic macrophages to control tumor metastasis.
Ding C, Shrestha R, Zhu X, Geller AE, Wu S, Woeste MR, Li W, Wang H, Yuan F, Xu R, Chariker JH, Hu X, Li H, Tieri D, Zhang HG, Rouchka EC, Mitchell R, Siskind LJ, Zhang X, Xu XG, McMasters KM, Yu Y, Yan J. Ding C, et al. Among authors: tieri d. Nat Immunol. 2023 Feb;24(2):239-254. doi: 10.1038/s41590-022-01388-8. Epub 2023 Jan 5. Nat Immunol. 2023. PMID: 36604547 Free PMC article.
Transcription factor c-Maf is a checkpoint that programs macrophages in lung cancer.
Liu M, Tong Z, Ding C, Luo F, Wu S, Wu C, Albeituni S, He L, Hu X, Tieri D, Rouchka EC, Hamada M, Takahashi S, Gibb AA, Kloecker G, Zhang HG, Bousamra M 2nd, Hill BG, Zhang X, Yan J. Liu M, et al. Among authors: tieri d. J Clin Invest. 2020 Apr 1;130(4):2081-2096. doi: 10.1172/JCI131335. J Clin Invest. 2020. PMID: 31945018 Free PMC article.
A specific low-density neutrophil population correlates with hypercoagulation and disease severity in hospitalized COVID-19 patients.
Morrissey SM, Geller AE, Hu X, Tieri D, Ding C, Klaes CK, Cooke EA, Woeste MR, Martin ZC, Chen O, Bush SE, Zhang HG, Cavallazzi R, Clifford SP, Chen J, Ghare S, Barve SS, Cai L, Kong M, Rouchka EC, McLeish KR, Uriarte SM, Watson CT, Huang J, Yan J. Morrissey SM, et al. Among authors: tieri d. JCI Insight. 2021 May 10;6(9):e148435. doi: 10.1172/jci.insight.148435. JCI Insight. 2021. PMID: 33986193 Free PMC article.
Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming.
Morrissey SM, Zhang F, Ding C, Montoya-Durango DE, Hu X, Yang C, Wang Z, Yuan F, Fox M, Zhang HG, Guo H, Tieri D, Kong M, Watson CT, Mitchell RA, Zhang X, McMasters KM, Huang J, Yan J. Morrissey SM, et al. Among authors: tieri d. Cell Metab. 2021 Oct 5;33(10):2040-2058.e10. doi: 10.1016/j.cmet.2021.09.002. Epub 2021 Sep 23. Cell Metab. 2021. PMID: 34559989 Free PMC article.
The induction of peripheral trained immunity in the pancreas incites anti-tumor activity to control pancreatic cancer progression.
Geller AE, Shrestha R, Woeste MR, Guo H, Hu X, Ding C, Andreeva K, Chariker JH, Zhou M, Tieri D, Watson CT, Mitchell RA, Zhang HG, Li Y, Martin Ii RCG, Rouchka EC, Yan J. Geller AE, et al. Among authors: tieri d. Nat Commun. 2022 Feb 9;13(1):759. doi: 10.1038/s41467-022-28407-4. Nat Commun. 2022. PMID: 35140221 Free PMC article.
15 results