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The influence of R substituents in triphenylphosphinegold(I) carbonimidothioates, Ph3PAu[SC(OR)=NPh] (R=Me, Et and iPr), upon in vitro cytotoxicity against the HT-29 colon cancer cell line and upon apoptotic pathways.
Yeo CI, Ooi KK, Akim AM, Ang KP, Fairuz ZA, Halim SN, Ng SW, Seng HL, Tiekink ER. Yeo CI, et al. Among authors: tiekink er. J Inorg Biochem. 2013 Oct;127:24-38. doi: 10.1016/j.jinorgbio.2013.05.011. Epub 2013 May 28. J Inorg Biochem. 2013. PMID: 23850666
Phosphanegold(I) dithiocarbamates, R3PAu[SC(=S)N((i)Pr)CH2CH2OH] for R = Ph, Cy and Et: role of phosphane-bound R substituents upon in vitro cytotoxicity against MCF-7R breast cancer cells and cell death pathways.
Jamaludin NS, Goh ZJ, Cheah YK, Ang KP, Sim JH, Khoo CH, Fairuz ZA, Halim SN, Ng SW, Seng HL, Tiekink ER. Jamaludin NS, et al. Among authors: tiekink er. Eur J Med Chem. 2013 Sep;67:127-41. doi: 10.1016/j.ejmech.2013.06.038. Epub 2013 Jun 26. Eur J Med Chem. 2013. PMID: 23856069
Phosphanegold(I) thiolates, Ph3PAu[SC(OR)=NC 6H 4Me-4] for R = Me, Et and iPr, induce apoptosis, cell cycle arrest and inhibit cell invasion of HT-29 colon cancer cells through modulation of the nuclear factor-κB activation pathway and ubiquitination.
Ooi KK, Yeo CI, Ang KP, Akim AM, Cheah YK, Halim SN, Seng HL, Tiekink ER. Ooi KK, et al. Among authors: tiekink er. J Biol Inorg Chem. 2015 Jul;20(5):855-73. doi: 10.1007/s00775-015-1271-5. Epub 2015 May 24. J Biol Inorg Chem. 2015. PMID: 26003312
853 results