Tidor B - Search Results

1

Design, synthesis, and biological and structural evaluations of novel HIV-1 protease inhibitors to combat drug resistance.

Parai MK, Huggins DJ, Cao H, Nalam MN, Ali A, Schiffer CA, Tidor B, Rana TM. Parai MK, et al. Among authors: tidor b. J Med Chem. 2012 Jul 26;55(14):6328-41. doi: 10.1021/jm300238h. Epub 2012 Jul 13. J Med Chem. 2012. PMID: 22708897 Free PMC article.

2

Additivity in the analysis and design of HIV protease inhibitors.

Jorissen RN, Reddy GS, Ali A, Altman MD, Chellappan S, Anjum SG, Tidor B, Schiffer CA, Rana TM, Gilson MK. Jorissen RN, et al. Among authors: tidor b. J Med Chem. 2009 Feb 12;52(3):737-54. doi: 10.1021/jm8009525. J Med Chem. 2009. PMID: 19193159 Free PMC article.

3

Evaluating the substrate-envelope hypothesis: structural analysis of novel HIV-1 protease inhibitors designed to be robust against drug resistance.

Nalam MN, Ali A, Altman MD, Reddy GS, Chellappan S, Kairys V, Ozen A, Cao H, Gilson MK, Tidor B, Rana TM, Schiffer CA. Nalam MN, et al. Among authors: tidor b. J Virol. 2010 May;84(10):5368-78. doi: 10.1128/JVI.02531-09. Epub 2010 Mar 17. J Virol. 2010. PMID: 20237088 Free PMC article.

4

Rational approaches to improving selectivity in drug design.

Huggins DJ, Sherman W, Tidor B. Huggins DJ, et al. Among authors: tidor b. J Med Chem. 2012 Feb 23;55(4):1424-44. doi: 10.1021/jm2010332. Epub 2012 Jan 12. J Med Chem. 2012. PMID: 22239221 Free PMC article. Review. No abstract available.

5

Substrate envelope-designed potent HIV-1 protease inhibitors to avoid drug resistance.

Nalam MN, Ali A, Reddy GS, Cao H, Anjum SG, Altman MD, Yilmaz NK, Tidor B, Rana TM, Schiffer CA. Nalam MN, et al. Among authors: tidor b. Chem Biol. 2013 Sep 19;20(9):1116-24. doi: 10.1016/j.chembiol.2013.07.014. Epub 2013 Sep 5. Chem Biol. 2013. PMID: 24012370 Free PMC article.

6

Computational design and experimental study of tighter binding peptides to an inactivated mutant of HIV-1 protease.

Altman MD, Nalivaika EA, Prabu-Jeyabalan M, Schiffer CA, Tidor B. Altman MD, et al. Among authors: tidor b. Proteins. 2008 Feb 15;70(3):678-94. doi: 10.1002/prot.21514. Proteins. 2008. PMID: 17729291 Free PMC article.

7

HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants.

Altman MD, Ali A, Reddy GS, Nalam MN, Anjum SG, Cao H, Chellappan S, Kairys V, Fernandes MX, Gilson MK, Schiffer CA, Rana TM, Tidor B. Altman MD, et al. Among authors: tidor b. J Am Chem Soc. 2008 May 14;130(19):6099-113. doi: 10.1021/ja076558p. Epub 2008 Apr 16. J Am Chem Soc. 2008. PMID: 18412349 Free PMC article.

8

Testing the substrate-envelope hypothesis with designed pairs of compounds.

Shen Y, Altman MD, Ali A, Nalam MN, Cao H, Rana TM, Schiffer CA, Tidor B. Shen Y, et al. Among authors: tidor b. ACS Chem Biol. 2013 Nov 15;8(11):2433-41. doi: 10.1021/cb400468c. Epub 2013 Sep 26. ACS Chem Biol. 2013. PMID: 23952265 Free PMC article.

9

Design of mutation-resistant HIV protease inhibitors with the substrate envelope hypothesis.

Chellappan S, Kiran Kumar Reddy GS, Ali A, Nalam MN, Anjum SG, Cao H, Kairys V, Fernandes MX, Altman MD, Tidor B, Rana TM, Schiffer CA, Gilson MK. Chellappan S, et al. Among authors: tidor b. Chem Biol Drug Des. 2007 May;69(5):298-313. doi: 10.1111/j.1747-0285.2007.00514.x. Chem Biol Drug Des. 2007. PMID: 17539822

10

Evaluation of an inverse molecular design algorithm in a model binding site.

Huggins DJ, Altman MD, Tidor B. Huggins DJ, et al. Among authors: tidor b. Proteins. 2009 Apr;75(1):168-86. doi: 10.1002/prot.22226. Proteins. 2009. PMID: 18831031 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

113 results

Search Page