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A reversible RNA on-switch that controls gene expression of AAV-delivered therapeutics in vivo.
Nat Biotechnol. 2020 Feb;38(2):169-175. doi: 10.1038/s41587-019-0357-y. Epub 2019 Dec 23.
Nat Biotechnol. 2020.
PMID: 31873216
Free PMC article.
Selection of High-Affinity RNA Aptamers That Distinguish between Doxycycline and Tetracycline.
Tickner ZJ, Zhong G, Sheptack KR, Farzan M.
Tickner ZJ, et al.
Biochemistry. 2020 Sep 22;59(37):3473-3486. doi: 10.1021/acs.biochem.0c00586. Epub 2020 Sep 6.
Biochemistry. 2020.
PMID: 32857495
Free PMC article.
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Riboswitches for Controlled Expression of Therapeutic Transgenes Delivered by Adeno-Associated Viral Vectors.
Tickner ZJ, Farzan M.
Tickner ZJ, et al.
Pharmaceuticals (Basel). 2021 Jun 10;14(6):554. doi: 10.3390/ph14060554.
Pharmaceuticals (Basel). 2021.
PMID: 34200913
Free PMC article.
Review.
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Correction: Tickner, Z.J.; Farzan, M. Riboswitches for Controlled Expression of Therapeutic Transgenes Delivered by Adeno-Associated Viral Vectors. Pharmaceuticals 2021, 14, 554.
Tickner ZJ, Farzan M.
Tickner ZJ, et al.
Pharmaceuticals (Basel). 2021 Dec 6;14(12):1271. doi: 10.3390/ph14121271.
Pharmaceuticals (Basel). 2021.
PMID: 34959739
Free PMC article.
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