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Carnosine synthase deficiency aggravates neuroinflammation in multiple sclerosis.
Spaas J, Van der Stede T, de Jager S, van de Waterweg Berends A, Tiane A, Baelde H, Baba SP, Eckhardt M, Wolfs E, Vanmierlo T, Hellings N, Eijnde BO, Derave W. Spaas J, et al. Among authors: tiane a. Prog Neurobiol. 2023 Dec;231:102532. doi: 10.1016/j.pneurobio.2023.102532. Epub 2023 Sep 27. Prog Neurobiol. 2023. PMID: 37774767
Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-β pathology.
Paes D, Schepers M, Willems E, Rombaut B, Tiane A, Solomina Y, Tibbo A, Blair C, Kyurkchieva E, Baillie GS, Ricciarelli R, Brullo C, Fedele E, Bruno O, van den Hove D, Vanmierlo T, Prickaerts J. Paes D, et al. Among authors: tiane a. Cell Mol Life Sci. 2023 Jun 12;80(7):178. doi: 10.1007/s00018-023-04804-w. Cell Mol Life Sci. 2023. PMID: 37306762 Free PMC article.
From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions.
Tiane A, Schepers M, Reijnders RA, van Veggel L, Chenine S, Rombaut B, Dempster E, Verfaillie C, Wasner K, Grünewald A, Prickaerts J, Pishva E, Hellings N, van den Hove D, Vanmierlo T. Tiane A, et al. Acta Neuropathol. 2023 Aug;146(2):283-299. doi: 10.1007/s00401-023-02596-8. Epub 2023 Jun 7. Acta Neuropathol. 2023. PMID: 37286732 Free PMC article.
Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis.
Schepers M, Paes D, Tiane A, Rombaut B, Piccart E, van Veggel L, Gervois P, Wolfs E, Lambrichts I, Brullo C, Bruno O, Fedele E, Ricciarelli R, Ffrench-Constant C, Bechler ME, van Schaik P, Baron W, Lefevere E, Wasner K, Grünewald A, Verfaillie C, Baeten P, Broux B, Wieringa P, Hellings N, Prickaerts J, Vanmierlo T. Schepers M, et al. Among authors: tiane a. Brain Behav Immun. 2023 Mar;109:1-22. doi: 10.1016/j.bbi.2022.12.020. Epub 2022 Dec 28. Brain Behav Immun. 2023. PMID: 36584795 Free article.
24(S)-Saringosterol Prevents Cognitive Decline in a Mouse Model for Alzheimer's Disease.
Martens N, Schepers M, Zhan N, Leijten F, Voortman G, Tiane A, Rombaut B, Poisquet J, Sande NV, Kerksiek A, Kuipers F, Jonker JW, Liu H, Lütjohann D, Vanmierlo T, Mulder MT. Martens N, et al. Among authors: tiane a. Mar Drugs. 2021 Mar 27;19(4):190. doi: 10.3390/md19040190. Mar Drugs. 2021. PMID: 33801706 Free PMC article.
Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders.
Spaas J, van Veggel L, Schepers M, Tiane A, van Horssen J, Wilson DM 3rd, Moya PR, Piccart E, Hellings N, Eijnde BO, Derave W, Schreiber R, Vanmierlo T. Spaas J, et al. Among authors: tiane a. Cell Mol Life Sci. 2021 May;78(10):4615-4637. doi: 10.1007/s00018-021-03802-0. Epub 2021 Mar 10. Cell Mol Life Sci. 2021. PMID: 33751149 Free PMC article. Review.
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