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Epithelial dysfunction is prevented by IL-22 treatment in a Citrobacter rodentium-induced colitis model that shares similarities with inflammatory bowel disease.
Zhu Q, Korenfeld D, Suarez-Fueyo A, Graham S, Jin L, Punit S, Duffy R, Puri M, Caruso A, Hu C, Tian Y, McRae BL, Kamath R, Phillips L, Schwartz-Sterman AJ, Westmoreland S, Cao X, Levesque MC, Bi Y, Paez-Cortez J, Goenka R. Zhu Q, et al. Among authors: tian y. Mucosal Immunol. 2022 Jun;15(6):1338-1349. doi: 10.1038/s41385-022-00577-w. Epub 2022 Nov 13. Mucosal Immunol. 2022. PMID: 36372810 Free article.
Identification of Plasma Biomarkers from Rheumatoid Arthritis Patients Using an Optimized Sequential Window Acquisition of All THeoretical Mass Spectra (SWATH) Proteomics Workflow.
Jin L, Wang F, Wang X, Harvey BP, Bi Y, Hu C, Cui B, Darcy AT, Maull JW, Phillips BR, Kim Y, Jenkins GJ, Sornasse TR, Tian Y. Jin L, et al. Among authors: tian y. Proteomes. 2023 Oct 16;11(4):32. doi: 10.3390/proteomes11040032. Proteomes. 2023. PMID: 37873874 Free PMC article.
Therapeutic TNF Inhibitors Exhibit Differential Levels of Efficacy in Accelerating Cutaneous Wound Healing.
Cao Y, Harvey BP, Jin L, Westmoreland S, Wang J, Puri M, Yang Y, Robb HM, Tanriverdi S, Hu C, Wang X, Xin X, Liu Y, Macoritto MP, Smith KM, Tian Y, White K, Radstake TRDJ, Kaymakcalan Z. Cao Y, et al. Among authors: tian y. JID Innov. 2023 Nov 25;4(1):100250. doi: 10.1016/j.xjidi.2023.100250. eCollection 2024 Jan. JID Innov. 2023. PMID: 38226320 Free PMC article.
An anti-TNF-glucocorticoid receptor modulator antibody-drug conjugate is efficacious against immune-mediated inflammatory diseases.
McPherson MJ, Hobson AD, Hernandez A Jr, Marvin CC, Waegell W, Goess C, Oh JZ, Shi D, Hayes ME, Wang L, Wang L, Schmidt D, Wang Z, Pitney V, McCarthy K, Jia Y, Wang C, Kang BN, Bryant S, Mathieu S, Ruzek M, Parmentier J, D'Cunha RR, Pang Y, Phillips L, Brown NJ, Xu J, Graff C, Tian Y, Longenecker KL, Qiu W, Zhu H, Liu W, Zheng P, Bi Y, Stoffel R. McPherson MJ, et al. Among authors: tian y. Sci Transl Med. 2024 Mar 20;16(739):eadd8936. doi: 10.1126/scitranslmed.add8936. Epub 2024 Mar 20. Sci Transl Med. 2024. PMID: 38507467
Self-Immolative Carbamate Linkers for CD19-Budesonide Antibody-Drug Conjugates.
Marvin CC, Hobson AD, McPherson M, Dunstan TA, Vargo TR, Hayes ME, Fettis MM, Bischoff A, Wang L, Wang L, Hernandez A Jr, Jia Y, Oh JZ, Tian Y. Marvin CC, et al. Among authors: tian y. Bioconjug Chem. 2023 Oct 18;34(10):1835-1850. doi: 10.1021/acs.bioconjchem.3c00354. Epub 2023 Oct 3. Bioconjug Chem. 2023. PMID: 37788373
Discovery of ABBV-154, an anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody-Drug Conjugate (iADC).
Hobson AD, Xu J, Welch DS, Marvin CC, McPherson MJ, Gates B, Liao X, Hollmann M, Gattner MJ, Dzeyk K, Sarvaiya H, Shenoy VM, Fettis MM, Bischoff AK, Wang L, Santora LC, Wang L, Fitzgibbons J, Salomon P, Hernandez A Jr, Jia Y, Goess CA, Mathieu SL, Bryant SH, Larsen ME, Cui B, Tian Y. Hobson AD, et al. Among authors: tian y. J Med Chem. 2023 Sep 14;66(17):12544-12558. doi: 10.1021/acs.jmedchem.3c01174. Epub 2023 Sep 1. J Med Chem. 2023. PMID: 37656698
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