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322 results

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Corticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo-a Meta-analysis of Individual Data From Controlled Trials.
Louvet A, Thursz MR, Kim DJ, Labreuche J, Atkinson SR, Sidhu SS, O'Grady JG, Akriviadis E, Sinakos E, Carithers RL Jr, Ramond MJ, Maddrey WC, Morgan TR, Duhamel A, Mathurin P. Louvet A, et al. Among authors: thursz mr. Gastroenterology. 2018 Aug;155(2):458-468.e8. doi: 10.1053/j.gastro.2018.05.011. Epub 2018 May 5. Gastroenterology. 2018. PMID: 29738698 Free article.
Prednisolone or pentoxifylline for alcoholic hepatitis.
Thursz MR, Richardson P, Allison M, Austin A, Bowers M, Day CP, Downs N, Gleeson D, MacGilchrist A, Grant A, Hood S, Masson S, McCune A, Mellor J, O'Grady J, Patch D, Ratcliffe I, Roderick P, Stanton L, Vergis N, Wright M, Ryder S, Forrest EH; STOPAH Trial. Thursz MR, et al. N Engl J Med. 2015 Apr 23;372(17):1619-28. doi: 10.1056/NEJMoa1412278. N Engl J Med. 2015. PMID: 25901427 Free article. Clinical Trial.
The clinical effectiveness and cost-effectiveness of STeroids Or Pentoxifylline for Alcoholic Hepatitis (STOPAH): a 2 × 2 factorial randomised controlled trial.
Thursz M, Forrest E, Roderick P, Day C, Austin A, O'Grady J, Ryder S, Allison M, Gleeson D, McCune A, Patch D, Wright M, Masson S, Richardson P, Vale L, Mellor J, Stanton L, Bowers M, Ratcliffe I, Downs N, Kirkman S, Homer T, Ternent L. Thursz M, et al. Health Technol Assess. 2015 Dec;19(102):1-104. doi: 10.3310/hta191020. Health Technol Assess. 2015. PMID: 26691209 Free PMC article. Clinical Trial.
Defective monocyte oxidative burst predicts infection in alcoholic hepatitis and is associated with reduced expression of NADPH oxidase.
Vergis N, Khamri W, Beale K, Sadiq F, Aletrari MO, Moore C, Atkinson SR, Bernsmeier C, Possamai LA, Petts G, Ryan JM, Abeles RD, James S, Foxton M, Hogan B, Foster GR, O'Brien AJ, Ma Y, Shawcross DL, Wendon JA, Antoniades CG, Thursz MR. Vergis N, et al. Among authors: thursz mr. Gut. 2017 Mar;66(3):519-529. doi: 10.1136/gutjnl-2015-310378. Epub 2016 Feb 9. Gut. 2017. PMID: 26860769 Free PMC article.
Treatment of Severe Alcoholic Hepatitis.
Thursz M, Morgan TR. Thursz M, et al. Gastroenterology. 2016 Jun;150(8):1823-34. doi: 10.1053/j.gastro.2016.02.074. Epub 2016 Mar 4. Gastroenterology. 2016. PMID: 26948886 Free PMC article. Review.
In Patients With Severe Alcoholic Hepatitis, Prednisolone Increases Susceptibility to Infection and Infection-Related Mortality, and Is Associated With High Circulating Levels of Bacterial DNA.
Vergis N, Atkinson SR, Knapp S, Maurice J, Allison M, Austin A, Forrest EH, Masson S, McCune A, Patch D, Richardson P, Gleeson D, Ryder SD, Wright M, Thursz MR. Vergis N, et al. Among authors: thursz mr. Gastroenterology. 2017 Apr;152(5):1068-1077.e4. doi: 10.1053/j.gastro.2016.12.019. Epub 2016 Dec 30. Gastroenterology. 2017. PMID: 28043903 Free PMC article. Clinical Trial.
322 results