Thummel KE - Search Results

1

Clinical Pharmacokinetic Assessment of Kratom (Mitragyna speciosa), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants.

Tanna RS, Nguyen JT, Hadi DL, Manwill PK, Flores-Bocanegra L, Layton ME, White JR, Cech NB, Oberlies NH, Rettie AE, Thummel KE, Paine MF. Tanna RS, et al. Among authors: thummel ke. Pharmaceutics. 2022 Mar 11;14(3):620. doi: 10.3390/pharmaceutics14030620. Pharmaceutics. 2022. PMID: 35335999 Free PMC article.

2

Purification of macaque liver flavin-containing monooxygenase: a form of the enzyme related immunochemically to an isozyme expressed selectively in adult human liver.

Sadeque AJ, Thummel KE, Rettie AE. Sadeque AJ, et al. Among authors: thummel ke. Biochim Biophys Acta. 1993 Mar 5;1162(1-2):127-34. doi: 10.1016/0167-4838(93)90138-h. Biochim Biophys Acta. 1993. PMID: 8448176

3

Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism.

Thummel KE, O'Shea D, Paine MF, Shen DD, Kunze KL, Perkins JD, Wilkinson GR. Thummel KE, et al. Clin Pharmacol Ther. 1996 May;59(5):491-502. doi: 10.1016/S0009-9236(96)90177-0. Clin Pharmacol Ther. 1996. PMID: 8646820 Clinical Trial.

4

First-pass metabolism of midazolam by the human intestine.

Paine MF, Shen DD, Kunze KL, Perkins JD, Marsh CL, McVicar JP, Barr DM, Gillies BS, Thummel KE. Paine MF, et al. Among authors: thummel ke. Clin Pharmacol Ther. 1996 Jul;60(1):14-24. doi: 10.1016/S0009-9236(96)90162-9. Clin Pharmacol Ther. 1996. PMID: 8689807

5

Fentanyl metabolism by human hepatic and intestinal cytochrome P450 3A4: implications for interindividual variability in disposition, efficacy, and drug interactions.

Labroo RB, Paine MF, Thummel KE, Kharasch ED. Labroo RB, et al. Among authors: thummel ke. Drug Metab Dispos. 1997 Sep;25(9):1072-80. Drug Metab Dispos. 1997. PMID: 9311623

6

Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism.

Paine MF, Khalighi M, Fisher JM, Shen DD, Kunze KL, Marsh CL, Perkins JD, Thummel KE. Paine MF, et al. Among authors: thummel ke. J Pharmacol Exp Ther. 1997 Dec;283(3):1552-62. J Pharmacol Exp Ther. 1997. PMID: 9400033

7

Comparison of CYP2D6 content and metoprolol oxidation between microsomes isolated from human livers and small intestines.

Madani S, Paine MF, Lewis L, Thummel KE, Shen DD. Madani S, et al. Among authors: thummel ke. Pharm Res. 1999 Aug;16(8):1199-205. doi: 10.1023/a:1018989211864. Pharm Res. 1999. PMID: 10468020

8

Immunoquantitation of FMO1 in human liver, kidney, and intestine.

Yeung CK, Lang DH, Thummel KE, Rettie AE. Yeung CK, et al. Among authors: thummel ke. Drug Metab Dispos. 2000 Sep;28(9):1107-11. Drug Metab Dispos. 2000. PMID: 10950857

9

Involvement of human cytochrome P450 2D6 in the bioactivation of acetaminophen.

Dong H, Haining RL, Thummel KE, Rettie AE, Nelson SD. Dong H, et al. Among authors: thummel ke. Drug Metab Dispos. 2000 Dec;28(12):1397-400. Drug Metab Dispos. 2000. PMID: 11095574

10

Can oral midazolam predict oral cyclosporine disposition?

Paine MF, Davis CL, Shen DD, Marsh CL, Raisys VA, Thummel KE. Paine MF, et al. Among authors: thummel ke. Eur J Pharm Sci. 2000 Nov;12(1):51-62. doi: 10.1016/s0928-0987(00)00139-1. Eur J Pharm Sci. 2000. PMID: 11121733

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