Thullier P - Search Results

1

Obtention and engineering of non-human primate (NHP) antibodies for therapeutics.

Pelat T, Hust M, Thullier P. Pelat T, et al. Among authors: thullier p. Mini Rev Med Chem. 2009 Dec;9(14):1633-8. doi: 10.2174/138955709791012283. Mini Rev Med Chem. 2009. PMID: 20105119 Review.

2

Germline humanization of a non-human primate antibody that neutralizes the anthrax toxin, by in vitro and in silico engineering.

Pelat T, Bedouelle H, Rees AR, Crennell SJ, Lefranc MP, Thullier P. Pelat T, et al. Among authors: thullier p. J Mol Biol. 2008 Dec 31;384(5):1400-7. doi: 10.1016/j.jmb.2008.10.033. Epub 2008 Oct 19. J Mol Biol. 2008. PMID: 18976662

3

[Recombinant antibodies against bioweapons].

Thullier P, Pelat T, Vidal D. Thullier P, et al. Med Sci (Paris). 2009 Dec;25(12):1145-8. doi: 10.1051/medsci/200925121145. Med Sci (Paris). 2009. PMID: 20035695 Free article. Review. French.

4

The humanness of macaque antibody sequences.

Thullier P, Huish O, Pelat T, Martin AC. Thullier P, et al. J Mol Biol. 2010 Mar 12;396(5):1439-50. doi: 10.1016/j.jmb.2009.12.041. Epub 2010 Jan 4. J Mol Biol. 2010. PMID: 20043919

5

Non-human primate immune libraries combined with germline humanization: an (almost) new, and powerful approach for the isolation of therapeutic antibodies.

Pelat T, Thullier P. Pelat T, et al. Among authors: thullier p. MAbs. 2009 Jul-Aug;1(4):377-81. doi: 10.4161/mabs.1.4.8635. Epub 2009 Jul 5. MAbs. 2009. PMID: 20068407 Free PMC article.

6

A comparison of human and macaque (Macaca mulatta) immunoglobulin germline V regions and its implications for antibody engineering.

Thullier P, Chahboun S, Pelat T. Thullier P, et al. MAbs. 2010 Sep-Oct;2(5):528-38. doi: 10.4161/mabs.2.5.12545. Epub 2010 Sep 1. MAbs. 2010. PMID: 20562531 Free PMC article.

7

Isolation of antibodies from non-human primates for clinical use.

Avril A, Froude JW, Mathieu J, Pelat T, Thullier P. Avril A, et al. Among authors: thullier p. Curr Drug Discov Technol. 2014 Mar;11(1):20-7. doi: 10.2174/15701638113109990030. Curr Drug Discov Technol. 2014. PMID: 23410051 Review.

8

High-affinity, human antibody-like antibody fragment (single-chain variable fragment) neutralizing the lethal factor (LF) of Bacillus anthracis by inhibiting protective antigen-LF complex formation.

Pelat T, Hust M, Laffly E, Condemine F, Bottex C, Vidal D, Lefranc MP, Dübel S, Thullier P. Pelat T, et al. Among authors: thullier p. Antimicrob Agents Chemother. 2007 Aug;51(8):2758-64. doi: 10.1128/AAC.01528-06. Epub 2007 May 21. Antimicrob Agents Chemother. 2007. PMID: 17517846 Free PMC article.

9

Improvement of an antibody neutralizing the anthrax toxin by simultaneous mutagenesis of its six hypervariable loops.

Laffly E, Pelat T, Cédrone F, Blésa S, Bedouelle H, Thullier P. Laffly E, et al. Among authors: thullier p. J Mol Biol. 2008 May 16;378(5):1094-103. doi: 10.1016/j.jmb.2008.03.045. Epub 2008 Mar 28. J Mol Biol. 2008. PMID: 18423488

10

Isolation of a human-like antibody fragment (scFv) that neutralizes ricin biological activity.

Pelat T, Hust M, Hale M, Lefranc MP, Dübel S, Thullier P. Pelat T, et al. Among authors: thullier p. BMC Biotechnol. 2009 Jun 30;9:60. doi: 10.1186/1472-6750-9-60. BMC Biotechnol. 2009. PMID: 19563687 Free PMC article.

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