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Novel Alzheimer risk genes determine the microglia response to amyloid-β but not to TAU pathology.
EMBO Mol Med. 2020 Mar 6;12(3):e10606. doi: 10.15252/emmm.201910606. Epub 2020 Jan 17.
EMBO Mol Med. 2020.
PMID: 31951107
Free PMC article.
The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques.
Sala Frigerio C, Wolfs L, Fattorelli N, Thrupp N, Voytyuk I, Schmidt I, Mancuso R, Chen WT, Woodbury ME, Srivastava G, Möller T, Hudry E, Das S, Saido T, Karran E, Hyman B, Perry VH, Fiers M, De Strooper B.
Sala Frigerio C, et al. Among authors: thrupp n.
Cell Rep. 2019 Apr 23;27(4):1293-1306.e6. doi: 10.1016/j.celrep.2019.03.099.
Cell Rep. 2019.
PMID: 31018141
Free PMC article.
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Single-Nucleus RNA-Seq Is Not Suitable for Detection of Microglial Activation Genes in Humans.
Thrupp N, Sala Frigerio C, Wolfs L, Skene NG, Fattorelli N, Poovathingal S, Fourne Y, Matthews PM, Theys T, Mancuso R, de Strooper B, Fiers M.
Thrupp N, et al.
Cell Rep. 2020 Sep 29;32(13):108189. doi: 10.1016/j.celrep.2020.108189.
Cell Rep. 2020.
PMID: 32997994
Free PMC article.
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Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer's disease.
Calafate S, Özturan G, Thrupp N, Vanderlinden J, Santa-Marinha L, Morais-Ribeiro R, Ruggiero A, Bozic I, Rusterholz T, Lorente-Echeverría B, Dias M, Chen WT, Fiers M, Lu A, Vlaeminck I, Creemers E, Craessaerts K, Vandenbempt J, van Boekholdt L, Poovathingal S, Davie K, Thal DR, Wierda K, Oliveira TG, Slutsky I, Adamantidis A, De Strooper B, de Wit J.
Calafate S, et al. Among authors: thrupp n.
Nat Neurosci. 2023 Jun;26(6):1021-1031. doi: 10.1038/s41593-023-01325-4. Epub 2023 May 15.
Nat Neurosci. 2023.
PMID: 37188873
Free PMC article.
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MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's disease.
Balusu S, Horré K, Thrupp N, Craessaerts K, Snellinx A, Serneels L, T'Syen D, Chrysidou I, Arranz AM, Sierksma A, Simrén J, Karikari TK, Zetterberg H, Chen WT, Thal DR, Salta E, Fiers M, De Strooper B.
Balusu S, et al. Among authors: thrupp n.
Science. 2023 Sep 15;381(6663):1176-1182. doi: 10.1126/science.abp9556. Epub 2023 Sep 14.
Science. 2023.
PMID: 37708272
Free PMC article.
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microRNA-132 regulates gene expression programs involved in microglial homeostasis.
Walgrave H, Penning A, Tosoni G, Snoeck S, Davie K, Davis E, Wolfs L, Sierksma A, Mars M, Bu T, Thrupp N, Zhou L, Moechars D, Mancuso R, Fiers M, Howden AJM, De Strooper B, Salta E.
Walgrave H, et al. Among authors: thrupp n.
iScience. 2023 May 6;26(6):106829. doi: 10.1016/j.isci.2023.106829. eCollection 2023 Jun 16.
iScience. 2023.
PMID: 37250784
Free PMC article.
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Development of the "Teamwork in Endoscopy Assessment Module for Endoscopic Non-Technical Skills" (TEAM-ENTS) behavioral marker system.
Ravindran S, Cavilla R, Ashrafian H, Haycock A, Healey C, Coleman M, Archer S, Darzi A, Thomas-Gibson S; TEAM-ENTS working group.
Ravindran S, et al.
Endoscopy. 2023 May;55(5):403-412. doi: 10.1055/a-1959-6123. Epub 2022 Oct 12.
Endoscopy. 2023.
PMID: 36223812
Review.
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Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer's disease.
Walgrave H, Balusu S, Snoeck S, Vanden Eynden E, Craessaerts K, Thrupp N, Wolfs L, Horré K, Fourne Y, Ronisz A, Silajdžić E, Penning A, Tosoni G, Callaerts-Vegh Z, D'Hooge R, Thal DR, Zetterberg H, Thuret S, Fiers M, Frigerio CS, De Strooper B, Salta E.
Walgrave H, et al. Among authors: thrupp n.
Cell Stem Cell. 2021 Oct 7;28(10):1805-1821.e8. doi: 10.1016/j.stem.2021.05.001. Epub 2021 May 24.
Cell Stem Cell. 2021.
PMID: 34033742
Free article.
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