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Sustained fetal hemoglobin induction in vivo is achieved by BCL11A interference and coexpressed truncated erythropoietin receptor.
Uchida N, Ferrara F, Drysdale CM, Yapundich M, Gamer J, Nassehi T, DiNicola J, Shibata Y, Wielgosz M, Kim YS, Bauler M, Throm RE, Haro-Mora JJ, Demirci S, Bonifacino AC, Krouse AE, Linde NS, Donahue RE, Ryu B, Tisdale JF. Uchida N, et al. Among authors: throm re. Sci Transl Med. 2021 Apr 28;13(591):eabb0411. doi: 10.1126/scitranslmed.abb0411. Sci Transl Med. 2021. PMID: 33910976
Production of Lentiviral Vectors Using Suspension Cells Grown in Serum-free Media.
Bauler M, Roberts JK, Wu CC, Fan B, Ferrara F, Yip BH, Diao S, Kim YI, Moore J, Zhou S, Wielgosz MM, Ryu B, Throm RE. Bauler M, et al. Among authors: throm re. Mol Ther Methods Clin Dev. 2019 Nov 26;17:58-68. doi: 10.1016/j.omtm.2019.11.011. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2019. PMID: 31890741 Free PMC article.
Lentiviral hematopoietic stem cell gene therapy for X-linked severe combined immunodeficiency.
De Ravin SS, Wu X, Moir S, Anaya-O'Brien S, Kwatemaa N, Littel P, Theobald N, Choi U, Su L, Marquesen M, Hilligoss D, Lee J, Buckner CM, Zarember KA, O'Connor G, McVicar D, Kuhns D, Throm RE, Zhou S, Notarangelo LD, Hanson IC, Cowan MJ, Kang E, Hadigan C, Meagher M, Gray JT, Sorrentino BP, Malech HL, Kardava L. De Ravin SS, et al. Among authors: throm re. Sci Transl Med. 2016 Apr 20;8(335):335ra57. doi: 10.1126/scitranslmed.aad8856. Sci Transl Med. 2016. PMID: 27099176 Free PMC article. Clinical Trial.
Antibody Responses to SARS-CoV-2 Antigens in Humans and Animals.
Kim H, Seiler P, Jones JC, Ridout G, Camp KP, Fabrizio TP, Jeevan T, Miller LA, Throm RE, Ferrara F, Fredrickson RL, Lowe JF, Wang L, Odemuyiwa SO, Wan XF, Webby RJ. Kim H, et al. Among authors: throm re. Vaccines (Basel). 2020 Nov 16;8(4):684. doi: 10.3390/vaccines8040684. Vaccines (Basel). 2020. PMID: 33207583 Free PMC article.
Integrome signatures of lentiviral gene therapy for SCID-X1 patients.
Yan KK, Condori J, Ma Z, Metais JY, Ju B, Ding L, Dhungana Y, Palmer LE, Langfitt DM, Ferrara F, Throm R, Shi H, Risch I, Bhatara S, Shaner B, Lockey TD, Talleur AC, Easton J, Meagher MM, Puck JM, Cowan MJ, Zhou S, Mamcarz E, Gottschalk S, Yu J. Yan KK, et al. Sci Adv. 2023 Oct 6;9(40):eadg9959. doi: 10.1126/sciadv.adg9959. Epub 2023 Oct 6. Sci Adv. 2023. PMID: 37801507 Free PMC article.
Route of 41BB/41BBL Costimulation Determines Effector Function of B7-H3-CAR.CD28ζ T Cells.
Nguyen P, Okeke E, Clay M, Haydar D, Justice J, O'Reilly C, Pruett-Miller S, Papizan J, Moore J, Zhou S, Throm R, Krenciute G, Gottschalk S, DeRenzo C. Nguyen P, et al. Mol Ther Oncolytics. 2020 Jun 23;18:202-214. doi: 10.1016/j.omto.2020.06.018. eCollection 2020 Sep 25. Mol Ther Oncolytics. 2020. PMID: 32728609 Free PMC article.
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