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449 results

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Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets.
Nacev BA, Sanchez-Vega F, Smith SA, Antonescu CR, Rosenbaum E, Shi H, Tang C, Socci ND, Rana S, Gularte-Mérida R, Zehir A, Gounder MM, Bowler TG, Luthra A, Jadeja B, Okada A, Strong JA, Stoller J, Chan JE, Chi P, D'Angelo SP, Dickson MA, Kelly CM, Keohan ML, Movva S, Thornton K, Meyers PA, Wexler LH, Slotkin EK, Glade Bender JL, Shukla NN, Hensley ML, Healey JH, La Quaglia MP, Alektiar KM, Crago AM, Yoon SS, Untch BR, Chiang S, Agaram NP, Hameed MR, Berger MF, Solit DB, Schultz N, Ladanyi M, Singer S, Tap WD. Nacev BA, et al. Among authors: thornton k. Nat Commun. 2022 Jun 15;13(1):3405. doi: 10.1038/s41467-022-30453-x. Nat Commun. 2022. PMID: 35705560 Free PMC article.
Clinical, genomic, and transcriptomic correlates of response to immune checkpoint blockade-based therapy in a cohort of patients with angiosarcoma treated at a single center.
Rosenbaum E, Antonescu CR, Smith S, Bradic M, Kashani D, Richards AL, Donoghue M, Kelly CM, Nacev B, Chan JE, Chi P, Dickson MA, Keohan ML, Gounder MM, Movva S, Avutu V, Thornton K, Zehir A, Bowman AS, Singer S, Tap W, D'Angelo S. Rosenbaum E, et al. Among authors: thornton k. J Immunother Cancer. 2022 Apr;10(4):e004149. doi: 10.1136/jitc-2021-004149. J Immunother Cancer. 2022. PMID: 35365586 Free PMC article.
Pilot study of bempegaldesleukin in combination with nivolumab in patients with metastatic sarcoma.
D'Angelo SP, Richards AL, Conley AP, Woo HJ, Dickson MA, Gounder M, Kelly C, Keohan ML, Movva S, Thornton K, Rosenbaum E, Chi P, Nacev B, Chan JE, Slotkin EK, Kiesler H, Adamson T, Ling L, Rao P, Patel S, Livingston JA, Singer S, Agaram NP, Antonescu CR, Koff A, Erinjeri JP, Hwang S, Qin LX, Donoghue MTA, Tap WD. D'Angelo SP, et al. Among authors: thornton k. Nat Commun. 2022 Jun 16;13(1):3477. doi: 10.1038/s41467-022-30874-8. Nat Commun. 2022. PMID: 35710741 Free PMC article. Clinical Trial.
Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor.
Slotkin EK, Bowman AS, Levine MF, Dela Cruz F, Coutinho DF, Sanchez GI, Rosales N, Modak S, Tap WD, Gounder MM, Thornton KA, Bouvier N, You D, Gundem G, Gerstle JT, Heaton TE, LaQuaglia MP, Wexler LH, Meyers PA, Kung AL, Papaemmanuil E, Zehir A, Ladanyi M, Shukla N. Slotkin EK, et al. Among authors: thornton ka. Mol Cancer Res. 2021 Jul;19(7):1146-1155. doi: 10.1158/1541-7786.MCR-20-0722. Epub 2021 Mar 22. Mol Cancer Res. 2021. PMID: 33753552 Free PMC article.
Long-term Follow-up and Patterns of Response, Progression, and Hyperprogression in Patients after PD-1 Blockade in Advanced Sarcoma.
Klemen ND, Hwang S, Bradic M, Rosenbaum E, Dickson MA, Gounder MM, Kelly CM, Keohan ML, Movva S, Thornton KA, Chi P, Nacev BA, Chan JE, Bartlett EK, Richards AL, Singer S, Donoghue MTA, Tap WD, D'Angelo SP. Klemen ND, et al. Among authors: thornton ka. Clin Cancer Res. 2022 Mar 1;28(5):939-947. doi: 10.1158/1078-0432.CCR-21-3445. Clin Cancer Res. 2022. PMID: 34965948 Free PMC article.
Phase II Trial of Imatinib Plus Binimetinib in Patients With Treatment-Naive Advanced Gastrointestinal Stromal Tumor.
Chi P, Qin LX, Nguyen B, Kelly CM, D'Angelo SP, Dickson MA, Gounder MM, Keohan ML, Movva S, Nacev BA, Rosenbaum E, Thornton KA, Crago AM, Yoon S, Ulaner G, Yeh R, Martindale M, Phelan HT, Biniakewitz MD, Warda S, Lee CJ, Berger MF, Schultz ND, Singer S, Hwang S, Chen Y, Antonescu CR, Tap WD. Chi P, et al. J Clin Oncol. 2022 Mar 20;40(9):997-1008. doi: 10.1200/JCO.21.02029. Epub 2022 Jan 18. J Clin Oncol. 2022. PMID: 35041493 Free PMC article. Clinical Trial.
Phase Ib Trial of the Combination of Imatinib and Binimetinib in Patients with Advanced Gastrointestinal Stromal Tumors.
Chi P, Qin LX, Camacho N, Kelly CM, D'Angelo SP, Dickson MA, Gounder MM, Keohan ML, Movva S, Nacev BA, Rosenbaum E, Thornton KA, Crago AM, Francis JH, Martindale M, Phelan HT, Biniakewitz MD, Lee CJ, Singer S, Hwang S, Berger MF, Chen Y, Antonescu CR, Tap WD. Chi P, et al. Clin Cancer Res. 2022 Apr 14;28(8):1507-1517. doi: 10.1158/1078-0432.CCR-21-3909. Clin Cancer Res. 2022. PMID: 35110417 Free PMC article. Clinical Trial.
State of the science: Uterine sarcomas: From pathology to practice.
Shushkevich A, Thaker PH, Littell RD, Shah NA, Chiang S, Thornton K, Hensley ML, Slomovitz BM, Holcomb KM, Leitao MM, Toboni MD, Powell MA, Levine DA, Dowdy SC, Klopp A, Brown J. Shushkevich A, et al. Among authors: thornton k. Gynecol Oncol. 2020 Oct;159(1):3-7. doi: 10.1016/j.ygyno.2020.08.008. Epub 2020 Aug 21. Gynecol Oncol. 2020. PMID: 32839026 No abstract available.
Pediatric soft tissue sarcomas.
Loeb DM, Thornton K, Shokek O. Loeb DM, et al. Among authors: thornton k. Surg Clin North Am. 2008 Jun;88(3):615-27, vii. doi: 10.1016/j.suc.2008.03.008. Surg Clin North Am. 2008. PMID: 18514702 Free PMC article. Review.
Management of extremity soft tissue sarcomas.
Hueman MT, Thornton K, Herman JM, Ahuja N. Hueman MT, et al. Among authors: thornton k. Surg Clin North Am. 2008 Jun;88(3):539-57, vi. doi: 10.1016/j.suc.2008.04.003. Surg Clin North Am. 2008. PMID: 18514697 Review.
449 results