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The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation.
Svedberg FR, Brown SL, Krauss MZ, Campbell L, Sharpe C, Clausen M, Howell GJ, Clark H, Madsen J, Evans CM, Sutherland TE, Ivens AC, Thornton DJ, Grencis RK, Hussell T, Cunoosamy DM, Cook PC, MacDonald AS. Svedberg FR, et al. Among authors: thornton dj. Nat Immunol. 2019 May;20(5):571-580. doi: 10.1038/s41590-019-0352-y. Epub 2019 Apr 1. Nat Immunol. 2019. PMID: 30936493 Free PMC article.
The major secreted protein of the whipworm parasite tethers to matrix and inhibits interleukin-13 function.
Bancroft AJ, Levy CW, Jowitt TA, Hayes KS, Thompson S, Mckenzie EA, Ball MD, Dubaissi E, France AP, Bellina B, Sharpe C, Mironov A, Brown SL, Cook PC, S MacDonald A, Thornton DJ, Grencis RK. Bancroft AJ, et al. Among authors: thornton dj. Nat Commun. 2019 May 28;10(1):2344. doi: 10.1038/s41467-019-09996-z. Nat Commun. 2019. PMID: 31138806 Free PMC article.
ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.
Campbell L, Hepworth MR, Whittingham-Dowd J, Thompson S, Bancroft AJ, Hayes KS, Shaw TN, Dickey BF, Flamar AL, Artis D, Schwartz DA, Evans CM, Roberts IS, Thornton DJ, Grencis RK. Campbell L, et al. Among authors: thornton dj. J Exp Med. 2019 Dec 2;216(12):2714-2723. doi: 10.1084/jem.20180610. Epub 2019 Oct 3. J Exp Med. 2019. PMID: 31582416 Free PMC article.
Trickle infection and immunity to Trichuris muris.
Glover M, Colombo SAP, Thornton DJ, Grencis RK. Glover M, et al. Among authors: thornton dj. PLoS Pathog. 2019 Nov 15;15(11):e1007926. doi: 10.1371/journal.ppat.1007926. eCollection 2019 Nov. PLoS Pathog. 2019. PMID: 31730667 Free PMC article.
177 results