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Mucins: the frontline defence of the lung.
Ridley C, Thornton DJ. Ridley C, et al. Among authors: thornton dj. Biochem Soc Trans. 2018 Oct 19;46(5):1099-1106. doi: 10.1042/BST20170402. Epub 2018 Aug 28. Biochem Soc Trans. 2018. PMID: 30154090 Free PMC article. Review.
Assembly of the respiratory mucin MUC5B: a new model for a gel-forming mucin.
Ridley C, Kouvatsos N, Raynal BD, Howard M, Collins RF, Desseyn JL, Jowitt TA, Baldock C, Davis CW, Hardingham TE, Thornton DJ. Ridley C, et al. Among authors: thornton dj. J Biol Chem. 2014 Jun 6;289(23):16409-20. doi: 10.1074/jbc.M114.566679. Epub 2014 Apr 28. J Biol Chem. 2014. PMID: 24778189 Free PMC article.
Assembly and organization of the N-terminal region of mucin MUC5AC: Indications for structural and functional distinction from MUC5B.
Carpenter J, Wang Y, Gupta R, Li Y, Haridass P, Subramani DB, Reidel B, Morton L, Ridley C, O'Neal WK, Buisine MP, Ehre C, Thornton DJ, Kesimer M. Carpenter J, et al. Among authors: thornton dj. Proc Natl Acad Sci U S A. 2021 Sep 28;118(39):e2104490118. doi: 10.1073/pnas.2104490118. Proc Natl Acad Sci U S A. 2021. PMID: 34548396 Free PMC article.
The normal trachea is cleaned by MUC5B mucin bundles from the submucosal glands coated with the MUC5AC mucin.
Ermund A, Meiss LN, Rodriguez-Pineiro AM, Bähr A, Nilsson HE, Trillo-Muyo S, Ridley C, Thornton DJ, Wine JJ, Hebert H, Klymiuk N, Hansson GC. Ermund A, et al. Among authors: thornton dj. Biochem Biophys Res Commun. 2017 Oct 21;492(3):331-337. doi: 10.1016/j.bbrc.2017.08.113. Epub 2017 Aug 30. Biochem Biophys Res Commun. 2017. PMID: 28859985 Free PMC article.
177 results