Thornton AM - Search Results

1

IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation.

Park SM, Cho H, Thornton AM, Barlowe TS, Chou T, Chhangawala S, Fairchild L, Taggart J, Chow A, Schurer A, Gruet A, Witkin MD, Kim JH, Shevach EM, Krivtsov A, Armstrong SA, Leslie C, Kharas MG. Park SM, et al. Among authors: thornton am. Cell Stem Cell. 2019 Jan 3;24(1):153-165.e7. doi: 10.1016/j.stem.2018.10.016. Epub 2018 Nov 21. Cell Stem Cell. 2019. PMID: 30472158 Free PMC article.

2

tTregs, pTregs, and iTregs: similarities and differences.

Shevach EM, Thornton AM. Shevach EM, et al. Among authors: thornton am. Immunol Rev. 2014 May;259(1):88-102. doi: 10.1111/imr.12160. Immunol Rev. 2014. PMID: 24712461 Free PMC article. Review.

3

Release of active TGF-β1 from the latent TGF-β1/GARP complex on T regulatory cells is mediated by integrin β8.

Edwards JP, Thornton AM, Shevach EM. Edwards JP, et al. Among authors: thornton am. J Immunol. 2014 Sep 15;193(6):2843-9. doi: 10.4049/jimmunol.1401102. Epub 2014 Aug 15. J Immunol. 2014. PMID: 25127859 Free PMC article.

4

Helios Deficiency Predisposes the Differentiation of CD4⁺Foxp3^- T Cells into Peripherally Derived Regulatory T Cells.

Skadow M, Penna VR, Galant-Swafford J, Shevach EM, Thornton AM. Skadow M, et al. Among authors: thornton am. J Immunol. 2019 Jul 15;203(2):370-378. doi: 10.4049/jimmunol.1900388. Epub 2019 Jun 5. J Immunol. 2019. PMID: 31167776 Free PMC article.

5

Helios: still behind the clouds.

Thornton AM, Shevach EM. Thornton AM, et al. Immunology. 2019 Nov;158(3):161-170. doi: 10.1111/imm.13115. Epub 2019 Oct 13. Immunology. 2019. PMID: 31517385 Free PMC article. Review.

6

Eos Is Redundant for Regulatory T Cell Function but Plays an Important Role in IL-2 and Th17 Production by CD4+ Conventional T Cells.

Rieder SA, Metidji A, Glass DD, Thornton AM, Ikeda T, Morgan BA, Shevach EM. Rieder SA, et al. Among authors: thornton am. J Immunol. 2015 Jul 15;195(2):553-63. doi: 10.4049/jimmunol.1500627. Epub 2015 Jun 10. J Immunol. 2015. PMID: 26062998 Free PMC article.

7

Helios Controls a Limited Subset of Regulatory T Cell Functions.

Sebastian M, Lopez-Ocasio M, Metidji A, Rieder SA, Shevach EM, Thornton AM. Sebastian M, et al. Among authors: thornton am. J Immunol. 2016 Jan 1;196(1):144-55. doi: 10.4049/jimmunol.1501704. Epub 2015 Nov 18. J Immunol. 2016. PMID: 26582951 Free PMC article.

8

Helios⁺ and Helios^- Treg subpopulations are phenotypically and functionally distinct and express dissimilar TCR repertoires.

Thornton AM, Lu J, Korty PE, Kim YC, Martens C, Sun PD, Shevach EM. Thornton AM, et al. Eur J Immunol. 2019 Mar;49(3):398-412. doi: 10.1002/eji.201847935. Epub 2019 Jan 15. Eur J Immunol. 2019. PMID: 30620397 Free PMC article.

9

Tregs, Helios and tumor immunity: the sun has not yet risen.

Thornton AM, Shevach EM. Thornton AM, et al. Transl Cancer Res. 2016 Oct;5(Suppl 4):S672-S674. doi: 10.21037/tcr.2016.10.47. Transl Cancer Res. 2016. PMID: 30637198 Free PMC article. No abstract available.

10

Selective deletion of Eos (Ikzf4) in T-regulatory cells leads to loss of suppressive function and development of systemic autoimmunity.

Gokhale AS, Gangaplara A, Lopez-Occasio M, Thornton AM, Shevach EM. Gokhale AS, et al. Among authors: thornton am. J Autoimmun. 2019 Dec;105:102300. doi: 10.1016/j.jaut.2019.06.011. Epub 2019 Jul 8. J Autoimmun. 2019. PMID: 31296356 Free PMC article.

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