Thorn P - Search Results

1

ABCA12 regulates insulin secretion from β-cells.

Ursino GM, Fu Y, Cottle DL, Mukhamedova N, Jones LK, Low H, Tham MS, Gan WJ, Mellett NA, Das PP, Weir JM, Ditiatkovski M, Fynch S, Thorn P, Thomas HE, Meikle PJ, Parkington HC, Smyth IM, Sviridov D. Ursino GM, et al. Among authors: thorn p. EMBO Rep. 2020 Mar 4;21(3):e48692. doi: 10.15252/embr.201948692. Epub 2020 Feb 18. EMBO Rep. 2020. PMID: 32072744 Free PMC article.

2

Local Integrin Activation in Pancreatic β Cells Targets Insulin Secretion to the Vasculature.

Gan WJ, Do OH, Cottle L, Ma W, Kosobrodova E, Cooper-White J, Bilek M, Thorn P. Gan WJ, et al. Among authors: thorn p. Cell Rep. 2018 Sep 11;24(11):2819-2826.e3. doi: 10.1016/j.celrep.2018.08.035. Cell Rep. 2018. PMID: 30208309 Free article.

3

Local activation of focal adhesion kinase orchestrates the positioning of presynaptic scaffold proteins and Ca²⁺ signalling to control glucose-dependent insulin secretion.

Jevon D, Deng K, Hallahan N, Kumar K, Tong J, Gan WJ, Tran C, Bilek M, Thorn P. Jevon D, et al. Among authors: thorn p. Elife. 2022 May 13;11:e76262. doi: 10.7554/eLife.76262. Elife. 2022. PMID: 35559734 Free PMC article.

4

Structural and functional polarisation of human pancreatic beta cells in islets from organ donors with and without type 2 diabetes.

Cottle L, Gan WJ, Gilroy I, Samra JS, Gill AJ, Loudovaris T, Thomas HE, Hawthorne WJ, Kebede MA, Thorn P. Cottle L, et al. Among authors: thorn p. Diabetologia. 2021 Mar;64(3):618-629. doi: 10.1007/s00125-020-05345-8. Epub 2021 Jan 5. Diabetologia. 2021. PMID: 33399909 Free PMC article.

5

Enhanced structure and function of human pluripotent stem cell-derived beta-cells cultured on extracellular matrix.

Singh R, Cottle L, Loudovaris T, Xiao D, Yang P, Thomas HE, Kebede MA, Thorn P. Singh R, et al. Among authors: thorn p. Stem Cells Transl Med. 2021 Mar;10(3):492-505. doi: 10.1002/sctm.20-0224. Epub 2020 Nov 4. Stem Cells Transl Med. 2021. PMID: 33145960 Free PMC article.

6

A fluorescent timer reporter enables sorting of insulin secretory granules by age.

Yau B, Hays L, Liang C, Laybutt DR, Thomas HE, Gunton JE, Williams L, Hawthorne WJ, Thorn P, Rhodes CJ, Kebede MA. Yau B, et al. Among authors: thorn p. J Biol Chem. 2020 Jul 3;295(27):8901-8911. doi: 10.1074/jbc.RA120.012432. Epub 2020 Apr 27. J Biol Chem. 2020. PMID: 32341128 Free PMC article.

7

Insulin secretion from beta cells in intact mouse islets is targeted towards the vasculature.

Low JT, Zavortink M, Mitchell JM, Gan WJ, Do OH, Schwiening CJ, Gaisano HY, Thorn P. Low JT, et al. Among authors: thorn p. Diabetologia. 2014 Aug;57(8):1655-63. doi: 10.1007/s00125-014-3252-6. Epub 2014 May 5. Diabetologia. 2014. PMID: 24795086 Free PMC article.

8

[No title available]

[No authors listed] [No authors listed] PMID: 33516488

9

Case Report: Hypoglycemia Due to a Novel Activating Glucokinase Variant in an Adult - a Molecular Approach.

Koneshamoorthy A, Seniveratne-Epa D, Calder G, Sawyer M, Kay TWH, Farrell S, Loudovaris T, Mariana L, McCarthy D, Lyu R, Liu X, Thorn P, Tong J, Chin LK, Zacharin M, Trainer A, Taylor S, MacIsaac RJ, Sachithanandan N, Thomas HE, Krishnamurthy B. Koneshamoorthy A, et al. Among authors: thorn p. Front Endocrinol (Lausanne). 2022 Mar 17;13:842937. doi: 10.3389/fendo.2022.842937. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35370948 Free PMC article.

10

Machine Learning Algorithms, Applied to Intact Islets of Langerhans, Demonstrate Significantly Enhanced Insulin Staining at the Capillary Interface of Human Pancreatic β Cells.

Cottle L, Gilroy I, Deng K, Loudovaris T, Thomas HE, Gill AJ, Samra JS, Kebede MA, Kim J, Thorn P. Cottle L, et al. Among authors: thorn p. Metabolites. 2021 Jun 7;11(6):363. doi: 10.3390/metabo11060363. Metabolites. 2021. PMID: 34200432 Free PMC article.

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