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Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation.
Martínez-Sánchez LDC, Ngo PA, Pradhan R, Becker LS, Boehringer D, Soteriou D, Kubankova M, Schweitzer C, Koch T, Thonn V, Erkert L, Stolzer I, Günther C, Becker C, Weigmann B, Klewer M, Daniel C, Amann K, Tenzer S, Atreya R, Bergo M, Brakebusch C, Watson AJM, Guck J, Fabry B, Atreya I, Neurath MF, López-Posadas R. Martínez-Sánchez LDC, et al. Among authors: thonn v. Gut. 2023 Feb;72(2):275-294. doi: 10.1136/gutjnl-2021-325520. Epub 2022 Mar 3. Gut. 2023. PMID: 35241625 Free PMC article.
Inhibiting PGGT1B Disrupts Function of RHOA, Resulting in T-cell Expression of Integrin α4β7 and Development of Colitis in Mice.
López-Posadas R, Fastancz P, Martínez-Sánchez LDC, Panteleev-Ivlev J, Thonn V, Kisseleva T, Becker LS, Schulz-Kuhnt A, Zundler S, Wirtz S, Atreya R, Carlé B, Friedrich O, Schürmann S, Waldner MJ, Neufert C, Brakebusch CH, Bergö MO, Neurath MF, Atreya I. López-Posadas R, et al. Among authors: thonn v. Gastroenterology. 2019 Nov;157(5):1293-1309. doi: 10.1053/j.gastro.2019.07.007. Epub 2019 Jul 11. Gastroenterology. 2019. PMID: 31302143 Free article.
Rho-A prenylation and signaling link epithelial homeostasis to intestinal inflammation.
López-Posadas R, Becker C, Günther C, Tenzer S, Amann K, Billmeier U, Atreya R, Fiorino G, Vetrano S, Danese S, Ekici AB, Wirtz S, Thonn V, Watson AJ, Brakebusch C, Bergö M, Neurath MF, Atreya I. López-Posadas R, et al. Among authors: thonn v. J Clin Invest. 2016 Feb;126(2):611-26. doi: 10.1172/JCI80997. Epub 2016 Jan 11. J Clin Invest. 2016. PMID: 26752649 Free PMC article.
Topical application of Chlorin e6-PVP (Ce6-PVP) for improved endoscopic detection of neoplastic lesions in a murine colitis-associated cancer model.
Ganzleben I, Hohmann M, Grünberg A, Gonzales-Menezes J, Vieth M, Liebing E, Günther C, Thonn V, Beß D, Becker C, Schmidt M, Neurath MF, Waldner MJ. Ganzleben I, et al. Among authors: thonn v. Sci Rep. 2020 Aug 4;10(1):13129. doi: 10.1038/s41598-020-69570-2. Sci Rep. 2020. PMID: 32753653 Free PMC article.
Severe Acute Respiratory Syndrome Coronavirus 2 Attachment Receptor Angiotensin-Converting Enzyme 2 Is Decreased in Crohn's Disease and Regulated By Microbial and Inflammatory Signaling.
Patankar JV, Chiriac MT, Lehmann M, Kühl AA, Atreya R, Becker C; Callaborators; Gonzalez-Acera M, Schmitt H, Gamez-Belmonte R, Mahapatro M, Diemand L, Hartmann L, Mascia F, Hracsko Z, Thonn V, Schödel L, Zielinska M, Yu Y, Erkert L, Li W, Zeitler M, Ruder B, Ganzleben I, Günther C, Voehringer D, Zundler S, Neurath MF, Siegmund B. Patankar JV, et al. Among authors: thonn v. Gastroenterology. 2021 Feb;160(3):925-928.e4. doi: 10.1053/j.gastro.2020.10.021. Epub 2020 Oct 17. Gastroenterology. 2021. PMID: 33075345 Free PMC article. No abstract available.
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