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Optogenetic control with a photocleavable protein, PhoCl.
Zhang W, Lohman AW, Zhuravlova Y, Lu X, Wiens MD, Hoi H, Yaganoglu S, Mohr MA, Kitova EN, Klassen JS, Pantazis P, Thompson RJ, Campbell RE. Zhang W, et al. Among authors: thompson rj. Nat Methods. 2017 Apr;14(4):391-394. doi: 10.1038/nmeth.4222. Epub 2017 Mar 13. Nat Methods. 2017. PMID: 28288123
A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells.
Billaud M, Chiu YH, Lohman AW, Parpaite T, Butcher JT, Mutchler SM, DeLalio LJ, Artamonov MV, Sandilos JK, Best AK, Somlyo AV, Thompson RJ, Le TH, Ravichandran KS, Bayliss DA, Isakson BE. Billaud M, et al. Among authors: thompson rj. Sci Signal. 2015 Feb 17;8(364):ra17. doi: 10.1126/scisignal.2005824. Sci Signal. 2015. PMID: 25690012 Free PMC article.
Constitutive SRC-mediated phosphorylation of pannexin 1 at tyrosine 198 occurs at the plasma membrane.
DeLalio LJ, Billaud M, Ruddiman CA, Johnstone SR, Butcher JT, Wolpe AG, Jin X, Keller TCS 4th, Keller AS, Rivière T, Good ME, Best AK, Lohman AW, Swayne LA, Penuela S, Thompson RJ, Lampe PD, Yeager M, Isakson BE. DeLalio LJ, et al. Among authors: thompson rj. J Biol Chem. 2019 Apr 26;294(17):6940-6956. doi: 10.1074/jbc.RA118.006982. Epub 2019 Feb 27. J Biol Chem. 2019. PMID: 30814251 Free PMC article.
Pannexin channels and ischaemia.
Thompson RJ. Thompson RJ. J Physiol. 2015 Aug 15;593(16):3463-70. doi: 10.1113/jphysiol.2014.282426. Epub 2014 Dec 2. J Physiol. 2015. PMID: 25384783 Free PMC article. Review.
Pannexin 1 activation and inhibition is permeant-selective.
Nielsen BS, Toft-Bertelsen TL, Lolansen SD, Anderson CL, Nielsen MS, Thompson RJ, MacAulay N. Nielsen BS, et al. Among authors: thompson rj. J Physiol. 2020 Jan;598(2):361-379. doi: 10.1113/JP278759. Epub 2020 Jan 6. J Physiol. 2020. PMID: 31698505 Free article.
Stress gates an astrocytic energy reservoir to impair synaptic plasticity.
Murphy-Royal C, Johnston AD, Boyce AKJ, Diaz-Castro B, Institoris A, Peringod G, Zhang O, Stout RF, Spray DC, Thompson RJ, Khakh BS, Bains JS, Gordon GR. Murphy-Royal C, et al. Among authors: thompson rj. Nat Commun. 2020 Apr 24;11(1):2014. doi: 10.1038/s41467-020-15778-9. Nat Commun. 2020. PMID: 32332733 Free PMC article.
595 results