Thompson PJ - Search Results

1

Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes.

Thompson PJ, Shah A, Ntranos V, Van Gool F, Atkinson M, Bhushan A. Thompson PJ, et al. Cell Metab. 2019 May 7;29(5):1045-1060.e10. doi: 10.1016/j.cmet.2019.01.021. Epub 2019 Feb 21. Cell Metab. 2019. PMID: 30799288 Free article.

2

β Cells led astray by transcription factors and the company they keep.

Thompson P, Bhushan A. Thompson P, et al. J Clin Invest. 2017 Jan 3;127(1):94-97. doi: 10.1172/JCI91304. Epub 2016 Dec 12. J Clin Invest. 2017. PMID: 27941244 Free PMC article.

3

BET Proteins Are Required for Transcriptional Activation of the Senescent Islet Cell Secretome in Type 1 Diabetes.

Thompson PJ, Shah A, Apostolopolou H, Bhushan A. Thompson PJ, et al. Int J Mol Sci. 2019 Sep 26;20(19):4776. doi: 10.3390/ijms20194776. Int J Mol Sci. 2019. PMID: 31561444 Free PMC article.

4

Invariant Natural Killer T cells coordinate removal of senescent cells.

Arora S, Thompson PJ, Wang Y, Bhattacharyya A, Apostolopoulou H, Hatano R, Naikawadi RP, Shah A, Wolters PJ, Koliwad S, Bhattacharya M, Bhushan A. Arora S, et al. Among authors: thompson pj. Med. 2021 Aug 13;2(8):938-950. doi: 10.1016/j.medj.2021.04.014. Epub 2021 May 10. Med. 2021. PMID: 34617070 Free PMC article.

5

DNA damage to β cells in culture recapitulates features of senescent β cells that accumulate in type 1 diabetes.

Brawerman G, Pipella J, Thompson PJ. Brawerman G, et al. Among authors: thompson pj. Mol Metab. 2022 Aug;62:101524. doi: 10.1016/j.molmet.2022.101524. Epub 2022 Jun 2. Mol Metab. 2022. PMID: 35660116 Free PMC article.

6

Alpha cell dysfunction in type 1 diabetes is independent of a senescence program.

Brawerman G, Ntranos V, Thompson PJ. Brawerman G, et al. Among authors: thompson pj. Front Endocrinol (Lausanne). 2022 Oct 7;13:932516. doi: 10.3389/fendo.2022.932516. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36277717 Free PMC article.

7

Stress-induced β cell early senescence confers protection against type 1 diabetes.

Lee H, Sahin GS, Chen CW, Sonthalia S, Cañas SM, Oktay HZ, Duckworth AT, Brawerman G, Thompson PJ, Hatzoglou M, Eizirik DL, Engin F. Lee H, et al. Among authors: thompson pj. Cell Metab. 2023 Dec 5;35(12):2200-2215.e9. doi: 10.1016/j.cmet.2023.10.014. Epub 2023 Nov 9. Cell Metab. 2023. PMID: 37949065 Free article.

8

Beta Cell Therapies for Preventing Type 1 Diabetes: From Bench to Bedside.

Brawerman G, Thompson PJ. Brawerman G, et al. Among authors: thompson pj. Biomolecules. 2020 Dec 16;10(12):1681. doi: 10.3390/biom10121681. Biomolecules. 2020. PMID: 33339173 Free PMC article. Review.

9

Pancreatic β-cell senescence in diabetes: mechanisms, markers and therapies.

Cha J, Aguayo-Mazzucato C, Thompson PJ. Cha J, et al. Among authors: thompson pj. Front Endocrinol (Lausanne). 2023 Aug 31;14:1212716. doi: 10.3389/fendo.2023.1212716. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37720527 Free PMC article. Review.

10

Editorial: Cellular senescence in diabetes: from markers to mechanisms and therapies.

Aguayo-Mazzucato C, Cha J, Thompson PJ. Aguayo-Mazzucato C, et al. Among authors: thompson pj. Front Endocrinol (Lausanne). 2023 Dec 18;14:1345529. doi: 10.3389/fendo.2023.1345529. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 38164496 Free PMC article. No abstract available.

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