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Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study.
Wechalekar A, Antoni G, Al Azzam W, Bergström M, Biswas S, Chen C, Cheriyan J, Cleveland M, Cookson L, Galette P, Janiczek RL, Kwong RY, Lukas MA, Millns H, Richards D, Schneider I, Solomon SD, Sörensen J, Storey J, Thompson D, van Dongen G, Vugts DJ, Wall A, Wikström G, Falk RH. Wechalekar A, et al. Among authors: thompson d. BMC Cardiovasc Disord. 2022 Feb 13;22(1):49. doi: 10.1186/s12872-021-02407-6. BMC Cardiovasc Disord. 2022. PMID: 35152886 Free PMC article. Clinical Trial.
Effect of ileal bile acid transporter inhibitor GSK2330672 on pruritus in primary biliary cholangitis: a double-blind, randomised, placebo-controlled, crossover, phase 2a study.
Hegade VS, Kendrick SF, Dobbins RL, Miller SR, Thompson D, Richards D, Storey J, Dukes GE, Corrigan M, Oude Elferink RP, Beuers U, Hirschfield GM, Jones DE. Hegade VS, et al. Among authors: thompson d. Lancet. 2017 Mar 18;389(10074):1114-1123. doi: 10.1016/S0140-6736(17)30319-7. Epub 2017 Feb 8. Lancet. 2017. PMID: 28187915 Clinical Trial.
Extracellular volume with bolus-only technique in amyloidosis patients: Diagnostic accuracy, correlation with other clinical cardiac measures, and ability to track changes in amyloid load over time.
Zumbo G, Barton SV, Thompson D, Sun M, Abdel-Gadir A, Treibel TA, Knight D, Martinez-Naharro A, Thirusha L, Gillmore JD, Moon JC, Hawkins PN, Fontana M. Zumbo G, et al. Among authors: thompson d. J Magn Reson Imaging. 2018 Jun;47(6):1677-1684. doi: 10.1002/jmri.25907. Epub 2017 Nov 21. J Magn Reson Imaging. 2018. PMID: 29159946
Loss of GPR75 protects against non-alcoholic fatty liver disease and body fat accumulation.
Leeson-Payne A, Iyinikkel J, Malcolm C, Lam BYH, Sommer N, Dowsett GKC, Martinez de Morentin PB, Thompson D, Mackenzie A, Chianese R, Kentistou K, Gardner EJ, Perry JRB, Grassmann F, Speakman JR, Rochford JJ, Yeo GSH, Murray F, Heisler LK. Leeson-Payne A, et al. Among authors: thompson d. Cell Metab. 2024 Apr 18:S1550-4131(24)00120-7. doi: 10.1016/j.cmet.2024.03.016. Online ahead of print. Cell Metab. 2024. PMID: 38653246
6,746 results