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Adeno-associated virus mediated expression of monoclonal antibody MR191 protects mice against Marburg virus and provides long-term expression in sheep.
Rghei AD, van Lieshout LP, Cao W, He S, Tierney K, Lopes JA, Zielinska N, Baracuhy EM, Campbell ESB, Minott JA, Guilleman MM, Hasson PC, Thompson B, Karimi K, Bridle BW, Susta L, Qiu X, Banadyga L, Wootton SK. Rghei AD, et al. Among authors: thompson b. Gene Ther. 2022 Sep 1. doi: 10.1038/s41434-022-00361-2. Online ahead of print. Gene Ther. 2022. PMID: 36050451
Safety and Tolerability of the Adeno-Associated Virus Vector, AAV6.2FF, Expressing a Monoclonal Antibody in Murine and Ovine Animal Models.
Rghei AD, van Lieshout LP, McLeod BM, Pei Y, Lopes JA, Zielinska N, Baracuhy EM, Stevens BAY, Thomas SP, Yates JGE, Warner BM, Kobasa D, Fausther-Bovendo H, Kobinger GP, Karimi K, Thompson B, Bridle BW, Susta L, Wootton SK. Rghei AD, et al. Among authors: thompson b. Biomedicines. 2021 Sep 9;9(9):1186. doi: 10.3390/biomedicines9091186. Biomedicines. 2021. PMID: 34572372 Free PMC article.
AAV-Vectored Expression of the Vascular Normalizing Agents 3TSR and Fc3TSR, and the Anti-Angiogenic Bevacizumab Extends Survival in a Murine Model of End-Stage Epithelial Ovarian Carcinoma.
Stegelmeier AA, Santry LA, Guilleman MM, Matuszewska K, Minott JA, Yates JGE, Stevens BAY, Thomas SP, Vanderkamp S, Hanada K, Pei Y, Rghei AD, van Vloten JP, Pereira M, Thompson B, Major PP, Petrik JJ, Bridle BW, Wootton SK. Stegelmeier AA, et al. Among authors: thompson b. Biomedicines. 2022 Feb 2;10(2):362. doi: 10.3390/biomedicines10020362. Biomedicines. 2022. PMID: 35203573 Free PMC article.
AAV-monoclonal antibody expression protects mice from Ebola virus without impeding the endogenous antibody response to heterologous challenge.
van Lieshout LP, Rghei AD, Cao W, He S, Soule G, Zhu W, Thomas SP, Sorensen D, Frost K, Tierney K, Thompson B, Booth S, Safronetz D, Kulkarni RR, Bridle BW, Qiu X, Banadyga L, Wootton SK. van Lieshout LP, et al. Among authors: thompson b. Mol Ther Methods Clin Dev. 2022 Aug 12;26:505-518. doi: 10.1016/j.omtm.2022.08.003. eCollection 2022 Sep 8. Mol Ther Methods Clin Dev. 2022. PMID: 36092367 Free PMC article.
3,597 results