Thomas WG - Search Results

1

Akt acts as a switch for GPCR transactivation of the TGF-β receptor type 1.

Mohamed R, Shajimoon A, Afroz R, Gabr M, Thomas WG, Little PJ, Kamato D. Mohamed R, et al. Among authors: thomas wg. FEBS J. 2022 May;289(9):2642-2656. doi: 10.1111/febs.16297. Epub 2021 Dec 18. FEBS J. 2022. PMID: 34826189 Free article.

2

Ga_q proteins: molecular pharmacology and therapeutic potential.

Kamato D, Mitra P, Davis F, Osman N, Chaplin R, Cabot PJ, Afroz R, Thomas W, Zheng W, Kaur H, Brimble M, Little PJ. Kamato D, et al. Cell Mol Life Sci. 2017 Apr;74(8):1379-1390. doi: 10.1007/s00018-016-2405-9. Epub 2016 Nov 4. Cell Mol Life Sci. 2017. PMID: 27815595 Review.

3

Unravelling the molecular complexity of GPCR-mediated EGFR transactivation using functional genomics approaches.

George AJ, Hannan RD, Thomas WG. George AJ, et al. Among authors: thomas wg. FEBS J. 2013 Nov;280(21):5258-68. doi: 10.1111/febs.12509. Epub 2013 Sep 23. FEBS J. 2013. PMID: 23992425 Free article. Review.

4

Endothelin-1 activates ETA receptors on human vascular smooth muscle cells to yield proteoglycans with increased binding to LDL.

Ballinger ML, Ivey ME, Osman N, Thomas WG, Little PJ. Ballinger ML, et al. Among authors: thomas wg. Atherosclerosis. 2009 Aug;205(2):451-7. doi: 10.1016/j.atherosclerosis.2009.01.024. Epub 2009 Jan 24. Atherosclerosis. 2009. PMID: 19217622

5

A functional siRNA screen identifies genes modulating angiotensin II-mediated EGFR transactivation.

George AJ, Purdue BW, Gould CM, Thomas DW, Handoko Y, Qian H, Quaife-Ryan GA, Morgan KA, Simpson KJ, Thomas WG, Hannan RD. George AJ, et al. Among authors: thomas wg, thomas dw. J Cell Sci. 2013 Dec 1;126(Pt 23):5377-90. doi: 10.1242/jcs.128280. Epub 2013 Sep 17. J Cell Sci. 2013. PMID: 24046455 Free PMC article.

6

Epidermal Growth Factor Receptor Transactivation: Mechanisms, Pathophysiology, and Potential Therapies in the Cardiovascular System.

Forrester SJ, Kawai T, O'Brien S, Thomas W, Harris RC, Eguchi S. Forrester SJ, et al. Annu Rev Pharmacol Toxicol. 2016;56:627-53. doi: 10.1146/annurev-pharmtox-070115-095427. Epub 2015 Nov 9. Annu Rev Pharmacol Toxicol. 2016. PMID: 26566153 Free PMC article.

7

BRET-based assay to monitor EGFR transactivation by the AT₁R reveals G_q/11 protein-independent activation and AT₁R-EGFR complexes.

O'Brien SL, Johnstone EKM, Devost D, Conroy J, Reichelt ME, Purdue BW, Ayoub MA, Kawai T, Inoue A, Eguchi S, Hébert TE, Pfleger KDG, Thomas WG. O'Brien SL, et al. Among authors: thomas wg. Biochem Pharmacol. 2018 Dec;158:232-242. doi: 10.1016/j.bcp.2018.10.017. Epub 2018 Oct 19. Biochem Pharmacol. 2018. PMID: 30347205 Free PMC article.

8

Transactivation of the epidermal growth factor receptor in responses to myocardial stress and cardioprotection.

Reichelt ME, O'Brien S, Thomas WG, Headrick JP. Reichelt ME, et al. Among authors: thomas wg. Int J Biochem Cell Biol. 2017 Feb;83:97-110. doi: 10.1016/j.biocel.2016.12.014. Epub 2016 Dec 31. Int J Biochem Cell Biol. 2017. PMID: 28049018 Review.

9

Adenoviral-directed expression of the type 1A angiotensin receptor promotes cardiomyocyte hypertrophy via transactivation of the epidermal growth factor receptor.

Thomas WG, Brandenburger Y, Autelitano DJ, Pham T, Qian H, Hannan RD. Thomas WG, et al. Circ Res. 2002 Feb 8;90(2):135-42. doi: 10.1161/hh0202.104109. Circ Res. 2002. PMID: 11834705

10

Complex interactions between the angiotensin II type 1 receptor, the epidermal growth factor receptor and TRIO-dependent signaling partners.

Johnstone EKM, Abhayawardana RS, See HB, Seeber RM, O'Brien SL, Thomas WG, Pfleger KDG. Johnstone EKM, et al. Among authors: thomas wg. Biochem Pharmacol. 2021 Jun;188:114521. doi: 10.1016/j.bcp.2021.114521. Epub 2021 Mar 17. Biochem Pharmacol. 2021. PMID: 33741329

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