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Local endothelial DNA repair deficiency causes aging-resembling endothelial-specific dysfunction.
Bautista-Niño PK, Portilla-Fernandez E, Rubio-Beltrán E, van der Linden JJ, de Vries R, van Veghel R, de Boer M, Durik M, Ridwan Y, Brandt R, Essers J, Menzies RI, Thomas R, de Bruin A, Duncker DJ, van Beusekom HMM, Ghanbari M, Hoeijmakers JHJ, Sedlacek R, Touyz RM, Montezano AC, van der Pluijm I, Danser AHJ, Haanes KA, Roks AJM. Bautista-Niño PK, et al. Among authors: thomas r. Clin Sci (Lond). 2020 Apr 17;134(7):727-746. doi: 10.1042/CS20190124. Clin Sci (Lond). 2020. PMID: 32202295
Hepatic Carbohydrate Response Element Binding Protein Activation Limits Nonalcoholic Fatty Liver Disease Development in a Mouse Model for Glycogen Storage Disease Type 1a.
Lei Y, Hoogerland JA, Bloks VW, Bos T, Bleeker A, Wolters H, Wolters JC, Hijmans BS, van Dijk TH, Thomas R, van Weeghel M, Mithieux G, Houtkooper RH, de Bruin A, Rajas F, Kuipers F, Oosterveer MH. Lei Y, et al. Among authors: thomas r. Hepatology. 2020 Nov;72(5):1638-1653. doi: 10.1002/hep.31198. Epub 2020 Oct 30. Hepatology. 2020. PMID: 32083759 Free PMC article.
Spontaneous liver disease in wild-type C57BL/6JOlaHsd mice fed semisynthetic diet.
Ronda OAHO, van de Heijning BJM, de Bruin A, Thomas RE, Martini I, Koehorst M, Gerding A, Koster MH, Bloks VW, Jurdzinski A, Mulder NL, Havinga R, van der Beek EM, Reijngoud DJ, Kuipers F, Verkade HJ. Ronda OAHO, et al. Among authors: thomas re. PLoS One. 2020 Sep 21;15(9):e0232069. doi: 10.1371/journal.pone.0232069. eCollection 2020. PLoS One. 2020. PMID: 32956351 Free PMC article.
Modeling Phenotypic Heterogeneity of Glycogen Storage Disease Type 1a Liver Disease in Mice by Somatic CRISPR/CRISPR-associated protein 9-Mediated Gene Editing.
Rutten MGS, Derks TGJ, Huijkman NCA, Bos T, Kloosterhuis NJ, van de Kolk KCWA, Wolters JC, Koster MH, Bongiovanni L, Thomas RE, de Bruin A, van de Sluis B, Oosterveer MH. Rutten MGS, et al. Hepatology. 2021 Nov;74(5):2491-2507. doi: 10.1002/hep.32022. Epub 2021 Aug 15. Hepatology. 2021. PMID: 34157136 Free PMC article.
Atypical E2Fs inhibit tumor angiogenesis.
Weijts BGMW, Westendorp B, Hien BT, Martínez-López LM, Zijp M, Thurlings I, Thomas RE, Schulte-Merker S, Bakker WJ, de Bruin A. Weijts BGMW, et al. Among authors: thomas re. Oncogene. 2018 Jan 11;37(2):271-276. doi: 10.1038/onc.2017.336. Epub 2017 Sep 18. Oncogene. 2018. PMID: 28925392 Free PMC article.
Normalization of hepatic ChREBP activity does not protect against liver disease progression in a mouse model for Glycogen Storage Disease type Ia.
Rutten MGS, Lei Y, Hoogerland JH, Bloks VW, Yang H, Bos T, Krishnamurthy KA, Bleeker A, Koster MH, Thomas RE, Wolters JC, van den Bos H, Mithieux G, Rajas F, Mardinoglu A, Spierings DCJ, de Bruin A, van de Sluis B, Oosterveer MH. Rutten MGS, et al. Cancer Metab. 2023 Apr 21;11(1):5. doi: 10.1186/s40170-023-00305-3. Cancer Metab. 2023. PMID: 37085901 Free PMC article.
8,228 results