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Low-dose penile SIVmac251 exposure of rhesus macaques infected with adenovirus type 5 (Ad5) and then immunized with a replication-defective Ad5-based SIV gag/pol/nef vaccine recapitulates the results of the phase IIb step trial of a similar HIV-1 vaccine.
Qureshi H, Ma ZM, Huang Y, Hodge G, Thomas MA, DiPasquale J, DeSilva V, Fritts L, Bett AJ, Casimiro DR, Shiver JW, Robert-Guroff M, Robertson MN, McChesney MB, Gilbert PB, Miller CJ. Qureshi H, et al. Among authors: ma zm, thomas ma. J Virol. 2012 Feb;86(4):2239-50. doi: 10.1128/JVI.06175-11. Epub 2011 Dec 7. J Virol. 2012. PMID: 22156519 Free PMC article. Clinical Trial.
Replicating adenovirus-simian immunodeficiency virus (SIV) recombinant priming and envelope protein boosting elicits localized, mucosal IgA immunity in rhesus macaques correlated with delayed acquisition following a repeated low-dose rectal SIV(mac251) challenge.
Xiao P, Patterson LJ, Kuate S, Brocca-Cofano E, Thomas MA, Venzon D, Zhao J, DiPasquale J, Fenizia C, Lee EM, Kalisz I, Kalyanaraman VS, Pal R, Montefiori D, Keele BF, Robert-Guroff M. Xiao P, et al. Among authors: thomas ma. J Virol. 2012 Apr;86(8):4644-57. doi: 10.1128/JVI.06812-11. Epub 2012 Feb 15. J Virol. 2012. PMID: 22345466 Free PMC article.
Effects of the deletion of early region 4 (E4) open reading frame 1 (orf1), orf1-2, orf1-3 and orf1-4 on virus-host cell interaction, transgene expression, and immunogenicity of replicating adenovirus HIV vaccine vectors.
Thomas MA, Song R, Demberg T, Vargas-Inchaustegui DA, Venzon D, Robert-Guroff M. Thomas MA, et al. PLoS One. 2013 Oct 15;8(10):e76344. doi: 10.1371/journal.pone.0076344. eCollection 2013. PLoS One. 2013. PMID: 24143187 Free PMC article.
HIV-1 CD4-induced (CD4i) gp120 epitope vaccines promote B and T-cell responses that contribute to reduced viral loads in rhesus macaques.
Thomas MA, Tuero I, Demberg T, Vargas-Inchaustegui DA, Musich T, Xiao P, Venzon D, LaBranche C, Montefiori DC, DiPasquale J, Reed SG, DeVico A, Fouts T, Lewis GK, Gallo RC, Robert-Guroff M. Thomas MA, et al. Virology. 2014 Dec;471-473:81-92. doi: 10.1016/j.virol.2014.10.001. Epub 2014 Oct 28. Virology. 2014. PMID: 25461534 Free PMC article.
E4orf1 Suppresses E1B-Deleted Adenovirus Vaccine-Induced Immune Responses.
Sangare K, Helmold Hait S, Moore M, Hogge C, Hoang T, Rahman MA, Venzon DJ, LaBranche C, Montefiori D, Robert-Guroff M, Thomas MA. Sangare K, et al. Among authors: thomas ma. Vaccines (Basel). 2022 Feb 15;10(2):295. doi: 10.3390/vaccines10020295. Vaccines (Basel). 2022. PMID: 35214753 Free PMC article.
717 results