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The novel histologic International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification system of lung adenocarcinoma is a stage-independent predictor of survival.
Warth A, Muley T, Meister M, Stenzinger A, Thomas M, Schirmacher P, Schnabel PA, Budczies J, Hoffmann H, Weichert W. Warth A, et al. Among authors: thomas m. J Clin Oncol. 2012 May 1;30(13):1438-46. doi: 10.1200/JCO.2011.37.2185. Epub 2012 Mar 5. J Clin Oncol. 2012. PMID: 22393100
EGFR, KRAS, BRAF and ALK gene alterations in lung adenocarcinomas: patient outcome, interplay with morphology and immunophenotype.
Warth A, Penzel R, Lindenmaier H, Brandt R, Stenzinger A, Herpel E, Goeppert B, Thomas M, Herth FJ, Dienemann H, Schnabel PA, Schirmacher P, Hoffmann H, Muley T, Weichert W. Warth A, et al. Among authors: thomas m. Eur Respir J. 2014 Mar;43(3):872-83. doi: 10.1183/09031936.00018013. Epub 2013 Aug 29. Eur Respir J. 2014. PMID: 23988776 Free article.
Synonymous EGFR variant p.Q787Q is neither prognostic nor predictive in patients with lung adenocarcinoma.
Leichsenring J, Volckmar AL, Magios N, Morais de Oliveira CM, Penzel R, Brandt R, Kirchner M, Bozorgmehr F, Thomas M, Schirmacher P, Warth A, Endris V, Stenzinger A. Leichsenring J, et al. Among authors: thomas m. Genes Chromosomes Cancer. 2017 Mar;56(3):214-220. doi: 10.1002/gcc.22427. Epub 2016 Nov 30. Genes Chromosomes Cancer. 2017. PMID: 27750395
Next-generation sequencing facilitates detection of the classic E13-A20 EML4-ALK fusion in an ALK-FISH/IHC inconclusive biopsy of a stage IV lung cancer patient: a case report.
Volckmar AL, Endris V, Bozorgmehr F, Lier C, Porcel C, Kirchner M, Leichsenring J, Penzel R, Thomas M, Schirmacher P, Warth A, Stenzinger A. Volckmar AL, et al. Among authors: thomas m. Diagn Pathol. 2016 Nov 18;11(1):133. doi: 10.1186/s13000-016-0581-4. Diagn Pathol. 2016. PMID: 27863497 Free PMC article.
AURKA, DLGAP5, TPX2, KIF11 and CKAP5: Five specific mitosis-associated genes correlate with poor prognosis for non-small cell lung cancer patients.
Schneider MA, Christopoulos P, Muley T, Warth A, Klingmueller U, Thomas M, Herth FJ, Dienemann H, Mueller NS, Theis F, Meister M. Schneider MA, et al. Among authors: thomas m. Int J Oncol. 2017 Feb;50(2):365-372. doi: 10.3892/ijo.2017.3834. Epub 2017 Jan 2. Int J Oncol. 2017. PMID: 28101582 Free PMC article.
EML4-ALK fusion variant V3 is a high-risk feature conferring accelerated metastatic spread, early treatment failure and worse overall survival in ALK+ non-small cell lung cancer.
Christopoulos P, Endris V, Bozorgmehr F, Elsayed M, Kirchner M, Ristau J, Buchhalter I, Penzel R, Herth FJ, Heussel CP, Eichhorn M, Muley T, Meister M, Fischer JR, Rieken S, Warth A, Bischoff H, Schirmacher P, Stenzinger A, Thomas M. Christopoulos P, et al. Among authors: thomas m. Int J Cancer. 2018 Jun 15;142(12):2589-2598. doi: 10.1002/ijc.31275. Epub 2018 Jan 24. Int J Cancer. 2018. PMID: 29363116 Free article.
Large cell neuroendocrine lung carcinoma induces peripheral T-cell repertoire alterations with predictive and prognostic significance.
Christopoulos P, Schneider MA, Bozorgmehr F, Kuon J, Engel-Riedel W, Kollmeier J, Baum V, Muley T, Schnabel PA, Bischoff H, Grohé C, Serke M, Thomas M, Fisch P, Meister M. Christopoulos P, et al. Among authors: thomas m. Lung Cancer. 2018 May;119:48-55. doi: 10.1016/j.lungcan.2018.03.002. Epub 2018 Mar 6. Lung Cancer. 2018. PMID: 29656752
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