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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 2
2005 4
2006 7
2007 2
2008 5
2009 8
2010 9
2011 6
2012 3
2013 4
2014 1
2015 9
2016 4
2017 5
2018 4
2019 4
2020 2
2021 5
2022 1
2024 0

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78 results

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Page 1
Structure-activity relationship studies of allosteric inhibitors of EYA2 tyrosine phosphatase.
Anantharajan J, Baburajendran N, Lin G, Loh YY, Xu W, Ahmad NHB, Liu S, Jansson AE, Kuan JWL, Ng EY, Yeo YK, Hung AW, Joy J, Hill J, Ford HL, Zhao R, Keller TH, Kang C. Anantharajan J, et al. Among authors: keller th. Protein Sci. 2022 Feb;31(2):422-431. doi: 10.1002/pro.4234. Epub 2021 Nov 18. Protein Sci. 2022. PMID: 34761455 Free PMC article.
Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe.
Zhang G, Dong Z, Gimple RC, Wolin A, Wu Q, Qiu Z, Wood LM, Shen JZ, Jiang L, Zhao L, Lv D, Prager BC, Kim LJY, Wang X, Zhang L, Anderson RL, Moore JK, Bao S, Keller TH, Lin G, Kang C, Hamerlik P, Zhao R, Ford HL, Rich JN. Zhang G, et al. Among authors: keller th. J Exp Med. 2021 Nov 1;218(11):e20202669. doi: 10.1084/jem.20202669. Epub 2021 Oct 7. J Exp Med. 2021. PMID: 34617969 Free PMC article.
Fragment-based lead discovery of indazole-based compounds as AXL kinase inhibitors.
Ng PS, Foo K, Sim S, Wang G, Huang C, Tan LH, Poulsen A, Liu B, Tee DHY, Ahmad NHB, Wang S, Ke Z, Lee MA, Kwek ZP, Joy J, Anantharajan J, Baburajendran N, Pendharkar V, Manoharan V, Vuddagiri S, Sangthongpitag K, Hill J, Keller TH, Hung AW. Ng PS, et al. Among authors: keller th. Bioorg Med Chem. 2021 Nov 1;49:116437. doi: 10.1016/j.bmc.2021.116437. Epub 2021 Sep 25. Bioorg Med Chem. 2021. PMID: 34600239
Strategic Design of Catalytic Lysine-Targeting Reversible Covalent BCR-ABL Inhibitors*.
Quach D, Tang G, Anantharajan J, Baburajendran N, Poulsen A, Wee JLK, Retna P, Li R, Liu B, Tee DHY, Kwek PZ, Joy JK, Yang WQ, Zhang CJ, Foo K, Keller TH, Yao SQ. Quach D, et al. Among authors: keller th. Angew Chem Int Ed Engl. 2021 Jul 26;60(31):17131-17137. doi: 10.1002/anie.202105383. Epub 2021 Jun 24. Angew Chem Int Ed Engl. 2021. PMID: 34008286
Probing biological mechanisms with chemical tools.
Kang C, Keller TH. Kang C, et al. Among authors: keller th. Pharmacol Res. 2020 Mar;153:104656. doi: 10.1016/j.phrs.2020.104656. Epub 2020 Jan 18. Pharmacol Res. 2020. PMID: 31962154 Review.
Stepwise Evolution of Fragment Hits against MAPK Interacting Kinases 1 and 2.
Kwiatkowski J, Liu B, Pang S, Ahmad NHB, Wang G, Poulsen A, Yang H, Poh YR, Tee DHY, Ong E, Retna P, Dinie N, Kwek P, Wee JLK, Manoharan V, Low CB, Seah PG, Pendharkar V, Sangthongpitag K, Joy J, Baburajendran N, Jansson AE, Nacro K, Hill J, Keller TH, Hung AW. Kwiatkowski J, et al. Among authors: keller th. J Med Chem. 2020 Jan 23;63(2):621-637. doi: 10.1021/acs.jmedchem.9b01582. Epub 2020 Jan 7. J Med Chem. 2020. PMID: 31910010
Correction to "Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3".
Huang C, Liew SS, Lin GR, Poulsen A, Ang MJY, Chia BCS, Chew SY, Kwek ZP, Wee JLK, Ong EH, Retna P, Baburajendran N, Li R, Yu W, Koh-Stenta X, Ngo A, Manesh S, Fulwood J, Ke Z, Chung HH, Sepramaniam S, Chew XH, Dinie N, Lee MA, Chew YS, Low CB, Pendharkar V, Manoharan V, Vuddagiri S, Sangthongpitag K, Joy J, Matter A, Hill J, Keller TH, Foo K. Huang C, et al. Among authors: keller th. ACS Med Chem Lett. 2019 Jul 9;10(8):1240. doi: 10.1021/acsmedchemlett.9b00278. eCollection 2019 Aug 8. ACS Med Chem Lett. 2019. PMID: 31413812 Free PMC article.
Structural and Functional Analyses of an Allosteric EYA2 Phosphatase Inhibitor That Has On-Target Effects in Human Lung Cancer Cells.
Anantharajan J, Zhou H, Zhang L, Hotz T, Vincent MY, Blevins MA, Jansson AE, Kuan JWL, Ng EY, Yeo YK, Baburajendran N, Lin G, Hung AW, Joy J, Patnaik S, Marugan J, Rudra P, Ghosh D, Hill J, Keller TH, Zhao R, Ford HL, Kang C. Anantharajan J, et al. Among authors: keller th. Mol Cancer Ther. 2019 Sep;18(9):1484-1496. doi: 10.1158/1535-7163.MCT-18-1239. Epub 2019 Jul 8. Mol Cancer Ther. 2019. PMID: 31285279 Free PMC article.
Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3.
Huang C, Liew SS, Lin GR, Poulsen A, Ang MJY, Chia BCS, Chew SY, Kwek ZP, Wee JLK, Ong EH, Retna P, Baburajendran N, Li R, Yu W, Koh-Stenta X, Ngo A, Manesh S, Fulwood J, Ke Z, Chung HH, Sepramaniam S, Chew XH, Dinie N, Lee MA, Chew YS, Low CB, Pendharkar V, Manoharan V, Vuddagiri S, Sangthongpitag K, Joy J, Matter A, Hill J, Keller TH, Foo K. Huang C, et al. Among authors: keller th. ACS Med Chem Lett. 2019 May 23;10(6):978-984. doi: 10.1021/acsmedchemlett.9b00170. eCollection 2019 Jun 13. ACS Med Chem Lett. 2019. PMID: 31223458 Free PMC article.
78 results