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A miRNA-145/TGF-β1 negative feedback loop regulates the cancer-associated fibroblast phenotype.
Melling GE, Flannery SE, Abidin SA, Clemmens H, Prajapati P, Hinsley EE, Hunt S, Catto JWF, Coletta RD, Mellone M, Thomas GJ, Parkinson EK, Prime SS, Paterson IC, Buttle DJ, Lambert DW. Melling GE, et al. Among authors: thomas gj. Carcinogenesis. 2018 May 28;39(6):798-807. doi: 10.1093/carcin/bgy032. Carcinogenesis. 2018. PMID: 29506142 Free article.
mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.
Herranz N, Gallage S, Mellone M, Wuestefeld T, Klotz S, Hanley CJ, Raguz S, Acosta JC, Innes AJ, Banito A, Georgilis A, Montoya A, Wolter K, Dharmalingam G, Faull P, Carroll T, Martínez-Barbera JP, Cutillas P, Reisinger F, Heikenwalder M, Miller RA, Withers D, Zender L, Thomas GJ, Gil J. Herranz N, et al. Among authors: thomas gj. Nat Cell Biol. 2015 Sep;17(9):1205-17. doi: 10.1038/ncb3225. Epub 2015 Aug 17. Nat Cell Biol. 2015. PMID: 26280535 Free PMC article.
A subset of myofibroblastic cancer-associated fibroblasts regulate collagen fiber elongation, which is prognostic in multiple cancers.
Hanley CJ, Noble F, Ward M, Bullock M, Drifka C, Mellone M, Manousopoulou A, Johnston HE, Hayden A, Thirdborough S, Liu Y, Smith DM, Mellows T, Kao WJ, Garbis SD, Mirnezami A, Underwood TJ, Eliceiri KW, Thomas GJ. Hanley CJ, et al. Among authors: thomas gj. Oncotarget. 2016 Feb 2;7(5):6159-74. doi: 10.18632/oncotarget.6740. Oncotarget. 2016. PMID: 26716418 Free PMC article.
Fibroblast activation and senescence in oral cancer.
Prime SS, Cirillo N, Hassona Y, Lambert DW, Paterson IC, Mellone M, Thomas GJ, James EN, Parkinson EK. Prime SS, et al. Among authors: thomas gj. J Oral Pathol Med. 2017 Feb;46(2):82-88. doi: 10.1111/jop.12456. Epub 2016 May 30. J Oral Pathol Med. 2017. PMID: 27237745 Review.
478 results