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mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma.
Thomas HE, Mercer CA, Carnevalli LS, Park J, Andersen JB, Conner EA, Tanaka K, Matsutani T, Iwanami A, Aronow BJ, Manway L, Maira SM, Thorgeirsson SS, Mischel PS, Thomas G, Kozma SC. Thomas HE, et al. Among authors: thomas g. Sci Transl Med. 2012 Jun 20;4(139):139ra84. doi: 10.1126/scitranslmed.3003923. Epub 2012 Apr 25. Sci Transl Med. 2012. PMID: 22539746 Free PMC article.
Mitochondrial Complex I Activity Is Required for Maximal Autophagy.
Thomas HE, Zhang Y, Stefely JA, Veiga SR, Thomas G, Kozma SC, Mercer CA. Thomas HE, et al. Among authors: thomas g. Cell Rep. 2018 Aug 28;24(9):2404-2417.e8. doi: 10.1016/j.celrep.2018.07.101. Cell Rep. 2018. PMID: 30157433 Free PMC article.
A liaison between mTOR signaling, ribosome biogenesis and cancer.
Gentilella A, Kozma SC, Thomas G. Gentilella A, et al. Among authors: thomas g. Biochim Biophys Acta. 2015 Jul;1849(7):812-20. doi: 10.1016/j.bbagrm.2015.02.005. Epub 2015 Feb 28. Biochim Biophys Acta. 2015. PMID: 25735853 Free PMC article. Review.
Effect of low doses of actinomycin D on neuroblastoma cell lines.
Cortes CL, Veiga SR, Almacellas E, Hernández-Losa J, Ferreres JC, Kozma SC, Ambrosio S, Thomas G, Tauler A. Cortes CL, et al. Among authors: thomas g. Mol Cancer. 2016 Jan 4;15:1. doi: 10.1186/s12943-015-0489-8. Mol Cancer. 2016. PMID: 26728659 Free PMC article.
A Phase Ib Study of the Dual PI3K/mTOR Inhibitor Dactolisib (BEZ235) Combined with Everolimus in Patients with Advanced Solid Malignancies.
Wise-Draper TM, Moorthy G, Salkeni MA, Karim NA, Thomas HE, Mercer CA, Beg MS, O'Gara S, Olowokure O, Fathallah H, Kozma SC, Thomas G, Rixe O, Desai P, Morris JC. Wise-Draper TM, et al. Among authors: thomas g, thomas he. Target Oncol. 2017 Jun;12(3):323-332. doi: 10.1007/s11523-017-0482-9. Target Oncol. 2017. PMID: 28357727 Free PMC article. Clinical Trial.
A compound directed against S6K1 hampers fat mass expansion and mitigates diet-induced hepatosteatosis.
Lluch A, Veiga SR, Latorre J, Moreno-Navarrete JM, Bonifaci N, Dien Nguyen V, Zhou Y, Höring M, Liebisch G, Olkkonen VM, Llobet-Navas D, Thomas G, Rodríguez-Barrueco R, Fernández-Real JM, Kozma SC, Ortega FJ. Lluch A, et al. Among authors: thomas g. JCI Insight. 2022 Jul 22;7(14):e150461. doi: 10.1172/jci.insight.150461. JCI Insight. 2022. PMID: 35737463 Free PMC article.
6,042 results