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Accumulation of JAK activation loop phosphorylation is linked to type I JAK inhibitor withdrawal syndrome in myelofibrosis.
Tvorogov D, Thomas D, Liau NPD, Dottore M, Barry EF, Lathi M, Kan WL, Hercus TR, Stomski F, Hughes TP, Tergaonkar V, Parker MW, Ross DM, Majeti R, Babon JJ, Lopez AF. Tvorogov D, et al. Among authors: thomas d. Sci Adv. 2018 Nov 28;4(11):eaat3834. doi: 10.1126/sciadv.aat3834. eCollection 2018 Nov. Sci Adv. 2018. PMID: 30498775 Free PMC article.
Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia.
Lewis AC, Pope VS, Tea MN, Li M, Nwosu GO, Nguyen TM, Wallington-Beddoe CT, Moretti PAB, Anderson D, Creek DJ, Costabile M, Ali SR, Thompson-Peach CAL, Dredge BK, Bert AG, Goodall GJ, Ekert PG, Brown AL, D'Andrea R, Robinson N, Pitman MR, Thomas D, Ross DM, Gliddon BL, Powell JA, Pitson SM. Lewis AC, et al. Among authors: thomas d, d andrea r. Blood. 2022 Jun 30;139(26):3737-3751. doi: 10.1182/blood.2021013277. Blood. 2022. PMID: 35443029 Free PMC article.
Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia.
Bassal MA, Samaraweera SE, Lim K, Benard BA, Bailey S, Kaur S, Leo P, Toubia J, Thompson-Peach C, Nguyen T, Maung KZY, Casolari DA, Iarossi DG, Pagani IS, Powell J, Pitson S, Natera S, Roessner U, Lewis ID, Brown AL, Tenen DG, Robinson N, Ross DM, Majeti R, Gonda TJ, Thomas D, D'Andrea RJ. Bassal MA, et al. Among authors: thomas d, d andrea rj. Nat Commun. 2022 May 12;13(1):2614. doi: 10.1038/s41467-022-30223-9. Nat Commun. 2022. PMID: 35551192 Free PMC article.
Author Correction: Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia.
Bassal MA, Samaraweera SE, Lim K, Benard BA, Bailey S, Kaur S, Leo P, Toubia J, Thompson-Peach C, Nguyen T, Maung KZY, Casolari DA, Iarossi DG, Pagani IS, Powell J, Pitson S, Natera S, Roessner U, Lewis ID, Brown AL, Tenen DG, Robinson N, Ross DM, Majeti R, Gonda TJ, Thomas D, D'Andrea RJ. Bassal MA, et al. Among authors: thomas d, d andrea rj. Nat Commun. 2022 Jul 15;13(1):4131. doi: 10.1038/s41467-022-31952-7. Nat Commun. 2022. PMID: 35840577 Free PMC article. No abstract available.
TP53 mutation in therapy-related myeloid neoplasm defines a distinct molecular subtype.
Hiwase D, Hahn C, Tran ENH, Chhetri R, Baranwal A, Al-Kali A, Sharplin K, Ladon D, Hollins R, Greipp P, Kutyna M, Alkhateeb H, Badar T, Wang P, Ross DM, Singhal D, Shanmuganathan N, Bardy P, Beligaswatte A, Yeung D, Litzow MR, Mangaonkar A, Giri P, Lee C, Yong A, Horvath N, Singhal N, Gowda R, Hogan W, Gangat N, Patnaik M, Begna K, Tiong IS, Wei A, Kumar S, Brown A, Scott H, Thomas D, Kok CH, Tefferi A, Shah MV. Hiwase D, et al. Among authors: thomas d. Blood. 2023 Mar 2;141(9):1087-1091. doi: 10.1182/blood.2022018236. Blood. 2023. PMID: 36574363 Free article. No abstract available.
Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia.
Kan WL, Dhagat U, Kaufmann KB, Hercus TR, Nero TL, Zeng AGX, Toubia J, Barry EF, Broughton SE, Gomez GA, Benard BA, Dottore M, Cheung Tung Shing KS, Boutzen H, Samaraweera SE, Simpson KJ, Jin L, Goodall GJ, Begley CG, Thomas D, Ekert PG, Tvorogov D, D'Andrea RJ, Dick JE, Parker MW, Lopez AF. Kan WL, et al. Among authors: thomas d, d andrea rj. Cancer Discov. 2023 Aug 4;13(8):1922-1947. doi: 10.1158/2159-8290.CD-22-1396. Cancer Discov. 2023. PMID: 37191437 Free PMC article.
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