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Design, Synthesis, and Characterization of I-BET567, a Pan-Bromodomain and Extra Terminal (BET) Bromodomain Oral Candidate.
Humphreys PG, Atkinson SJ, Bamborough P, Bit RA, Chung CW, Craggs PD, Cutler L, Davis R, Ferrie A, Gong G, Gordon LJ, Gray M, Harrison LA, Hayhow TG, Haynes A, Henley N, Hirst DJ, Holyer ID, Lindon MJ, Lovatt C, Lugo D, McCleary S, Molnar J, Osmani Q, Patten C, Preston A, Rioja I, Seal JT, Smithers N, Sun F, Tang D, Taylor S, Theodoulou NH, Thomas C, Watson RJ, Wellaway CR, Zhu L, Tomkinson NCO, Prinjha RK. Humphreys PG, et al. Among authors: thomas c. J Med Chem. 2022 Feb 10;65(3):2262-2287. doi: 10.1021/acs.jmedchem.1c01747. Epub 2022 Jan 7. J Med Chem. 2022. PMID: 34995458 Free article.
Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase.
Cheng Z, Aitha M, Thomas CA, Sturgill A, Fairweather M, Hu A, Bethel CR, Rivera DD, Dranchak P, Thomas PW, Li H, Feng Q, Tao K, Song M, Sun N, Wang S, Silwal SB, Page RC, Fast W, Bonomo RA, Weese M, Martinez W, Inglese J, Crowder MW. Cheng Z, et al. Among authors: thomas ca. J Chem Inf Model. 2024 May 10. doi: 10.1021/acs.jcim.3c02015. Online ahead of print. J Chem Inf Model. 2024. PMID: 38727192
Anesthetic Oxygen Use and Sex Are Critical Factors in the FLASH Sparing Effect.
Tavakkoli AD, Clark MA, Kheirollah A, Sloop AM, Soderholm HE, Daniel NJ, Petusseau AF, Huang YH, Thomas CR Jr, Jarvis LA, Zhang R, Pogue BW, Gladstone DJ, Hoopes PJ. Tavakkoli AD, et al. Among authors: thomas cr jr. Adv Radiat Oncol. 2024 Mar 13;9(6):101492. doi: 10.1016/j.adro.2024.101492. eCollection 2024 Jun. Adv Radiat Oncol. 2024. PMID: 38711960 Free PMC article.
Long-term Musculoskeletal Consequences of Chemotherapy in Pediatric Mice.
Huot JR, Livingston PD, Pin F, Thomas CR, Jamnick NA, Callaway CS, Bonetto A. Huot JR, et al. Among authors: thomas cr. Function (Oxf). 2024 Mar 7;5(3):zqae011. doi: 10.1093/function/zqae011. eCollection 2024. Function (Oxf). 2024. PMID: 38706958 Free PMC article.
Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas.
Choi J, Ceribelli M, Phelan JD, Häupl B, Huang DW, Wright GW, Hsiao T, Morris V, Ciccarese F, Wang B, Corcoran S, Scheich S, Yu X, Xu W, Yang Y, Zhao H, Zhou J, Zhang G, Muppidi J, Inghirami GG, Oellerich T, Wilson WH, Thomas CJ, Staudt LM. Choi J, et al. Among authors: thomas cj. Cancer Cell. 2024 May 2:S1535-6108(24)00131-4. doi: 10.1016/j.ccell.2024.04.007. Online ahead of print. Cancer Cell. 2024. PMID: 38701792
8,393 results