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Pharmacological inhibition of TBK1/IKKε blunts immunopathology in a murine model of SARS-CoV-2 infection.
Ullah TR, Johansen MD, Balka KR, Ambrose RL, Gearing LJ, Roest J, Vivian JP, Sapkota S, Jayasekara WSN, Wenholz DS, Aldilla VR, Zeng J, Miemczyk S, Nguyen DH, Hansbro NG, Venkatraman R, Kang JH, Pang ES, Thomas BJ, Alharbi AS, Rezwan R, O'Keeffe M, Donald WA, Ellyard JI, Wong W, Kumar N, Kile BT, Vinuesa CG, Kelly GE, Laczka OF, Hansbro PM, De Nardo D, Gantier MP. Ullah TR, et al. Among authors: thomas bj. Nat Commun. 2023 Sep 18;14(1):5666. doi: 10.1038/s41467-023-41381-9. Nat Commun. 2023. PMID: 37723181 Free PMC article.
Genistein Targets STING-Driven Antiviral Responses.
Ullah TR, Balka KR, Ambrose RL, Pépin G, Wilce MCJ, Wilce JA, Thomas BJ, De Nardo D, Williams BRG, Gantier MP. Ullah TR, et al. Among authors: thomas bj. mBio. 2022 Aug 30;13(4):e0206422. doi: 10.1128/mbio.02064-22. Epub 2022 Aug 4. mBio. 2022. PMID: 35924852 Free PMC article.
Activation of cGAS-dependent antiviral responses by DNA intercalating agents.
Pépin G, Nejad C, Thomas BJ, Ferrand J, McArthur K, Bardin PG, Williams BR, Gantier MP. Pépin G, et al. Among authors: thomas bj. Nucleic Acids Res. 2017 Jan 9;45(1):198-205. doi: 10.1093/nar/gkw878. Epub 2016 Sep 29. Nucleic Acids Res. 2017. PMID: 27694309 Free PMC article.
The immune receptor NOD1 and kinase RIP2 interact with bacterial peptidoglycan on early endosomes to promote autophagy and inflammatory signaling.
Irving AT, Mimuro H, Kufer TA, Lo C, Wheeler R, Turner LJ, Thomas BJ, Malosse C, Gantier MP, Casillas LN, Votta BJ, Bertin J, Boneca IG, Sasakawa C, Philpott DJ, Ferrero RL, Kaparakis-Liaskos M. Irving AT, et al. Among authors: thomas bj. Cell Host Microbe. 2014 May 14;15(5):623-35. doi: 10.1016/j.chom.2014.04.001. Epub 2014 Apr 17. Cell Host Microbe. 2014. PMID: 24746552 Free article.
Nontypeable Haemophilus influenzae induces sustained lung oxidative stress and protease expression.
King PT, Sharma R, O'Sullivan K, Selemidis S, Lim S, Radhakrishna N, Lo C, Prasad J, Callaghan J, McLaughlin P, Farmer M, Steinfort D, Jennings B, Ngui J, Broughton BR, Thomas B, Essilfie AT, Hickey M, Holmes PW, Hansbro P, Bardin PG, Holdsworth SR. King PT, et al. PLoS One. 2015 Mar 20;10(3):e0120371. doi: 10.1371/journal.pone.0120371. eCollection 2015. PLoS One. 2015. PMID: 25793977 Free PMC article.
Mitochondrially localised MUL1 is a novel modulator of antiviral signaling.
Jenkins K, Khoo JJ, Sadler A, Piganis R, Wang D, Borg NA, Hjerrild K, Gould J, Thomas BJ, Nagley P, Hertzog PJ, Mansell A. Jenkins K, et al. Among authors: thomas bj. Immunol Cell Biol. 2013 Apr;91(4):321-30. doi: 10.1038/icb.2013.7. Epub 2013 Feb 12. Immunol Cell Biol. 2013. PMID: 23399697
441 results