Thoma G - Search Results

1

Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane.

Zamprogno P, Wüthrich S, Achenbach S, Thoma G, Stucki JD, Hobi N, Schneider-Daum N, Lehr CM, Huwer H, Geiser T, Schmid RA, Guenat OT. Zamprogno P, et al. Among authors: thoma g. Commun Biol. 2021 Feb 5;4(1):168. doi: 10.1038/s42003-021-01695-0. Commun Biol. 2021. PMID: 33547387 Free PMC article.

2

Mechanical Properties of Soft Biological Membranes for Organ-on-a-Chip Assessed by Bulge Test and AFM.

Zamprogno P, Thoma G, Cencen V, Ferrari D, Putz B, Michler J, Fantner GE, Guenat OT. Zamprogno P, et al. Among authors: thoma g. ACS Biomater Sci Eng. 2021 Jul 12;7(7):2990-2997. doi: 10.1021/acsbiomaterials.0c00515. Epub 2021 Mar 2. ACS Biomater Sci Eng. 2021. PMID: 33651947 Free article.

3

Structure-Guided Elaboration of a Fragment-Like Hit into an Orally Efficacious Leukotriene A4 Hydrolase Inhibitor.

Thoma G, Miltz W, Srinivas H, Penno CA, Kiffe M, Gajewska M, Klein K, Evans A, Beerli C, Röhn TA. Thoma G, et al. J Med Chem. 2024 Mar 28;67(6):5093-5108. doi: 10.1021/acs.jmedchem.4c00290. Epub 2024 Mar 12. J Med Chem. 2024. PMID: 38476002

4

LTA4H inhibitor LYS006: Clinical PK/PD and safety in a randomized phase I clinical trial.

Loesche C, Picard D, Van Hoorick B, Schuhmann I, Jäger P, Klein K, Schuhler C, Thoma G, Markert C, Poller B, Zamurovic N, Weiss HM, Otto H, Fink M, Röhn TA. Loesche C, et al. Among authors: thoma g. Clin Transl Sci. 2024 Feb;17(2):e13724. doi: 10.1111/cts.13724. Clin Transl Sci. 2024. PMID: 38407540 Free PMC article. Clinical Trial.

5

Fifty years of environmental progress for United States dairy farms.

Rotz CA, Beegle D, Bernard JK, Leytem A, Feyereisen G, Hagevoort R, Harrison J, Aksland G, Thoma G. Rotz CA, et al. Among authors: thoma g. J Dairy Sci. 2024 Jan 10:S0022-0302(24)00010-9. doi: 10.3168/jds.2023-24185. Online ahead of print. J Dairy Sci. 2024. PMID: 38216038 Free article.

6

The Effect of Laterality in Modified Radical Neck Dissection on the Risk of Intraoperative Bradycardia: A Retrospective Cohort Study.

Mitos G, Soteriades S, Katsakis-Giannakis Z, Perente M, Thoma G, Sarridou D. Mitos G, et al. Among authors: thoma g. Cureus. 2023 Dec 7;15(12):e50129. doi: 10.7759/cureus.50129. eCollection 2023 Dec. Cureus. 2023. PMID: 38186531 Free PMC article.

7

Discovery of Amino Alcohols as Highly Potent, Selective, and Orally Efficacious Inhibitors of Leukotriene A4 Hydrolase.

Thoma G, Markert C, Lueoend R, Miltz W, Spanka C, Bollbuck B, Wolf RM, Srinivas H, Penno CA, Kiffe M, Gajewska M, Bednarczyk D, Wieczorek G, Evans A, Beerli C, Röhn TA. Thoma G, et al. J Med Chem. 2023 Dec 14;66(23):16410-16425. doi: 10.1021/acs.jmedchem.3c01866. Epub 2023 Nov 28. J Med Chem. 2023. PMID: 38015154

8

Design of a Supersoft Topical JAK Inhibitor, Which Is Effective in Human Skin but Rapidly Deactivated in Blood.

Thoma G, Decoret O, Vangrevelinghe E, Trunzer M, Decker A, Orjuela Leon A, Beerli C, Bruno S, Hauchard A, Paulat G, Zerwes HG, Hacini-Rachinel F. Thoma G, et al. J Med Chem. 2023 Nov 9;66(21):15042-15053. doi: 10.1021/acs.jmedchem.3c01735. Epub 2023 Oct 31. J Med Chem. 2023. PMID: 37906573

9

From Microanalysis to Atomic Electron Pair Distribution Function (ePDF): Adding Another Degree of Freedom in Analyzing Nanoscale Materials.

Liu Y, Buckett MI, Jin GB, Burch MJ, Rosas AS, Thoma GM, Steinbach AJ. Liu Y, et al. Among authors: thoma gm. Microsc Microanal. 2023 Jul 22;29(Supplement_1):1750-1751. doi: 10.1093/micmic/ozad067.905. Microsc Microanal. 2023. PMID: 37613919 No abstract available.

10

Novel Concept for Super-Soft Topical Drugs: Deactivation by an Enzyme-Induced Switch into an Inactive Conformation.

Thoma G, Vangrevelinghe E, Luneau A, Piechon P, Beerli C, Zerwes HG. Thoma G, et al. ACS Med Chem Lett. 2023 May 30;14(6):841-845. doi: 10.1021/acsmedchemlett.3c00169. eCollection 2023 Jun 8. ACS Med Chem Lett. 2023. PMID: 37312861

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