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Ca2+ entry via TRPC channels is necessary for thrombin-induced NF-kappaB activation in endothelial cells through AMP-activated protein kinase and protein kinase Cdelta.
Bair AM, Thippegowda PB, Freichel M, Cheng N, Ye RD, Vogel SM, Yu Y, Flockerzi V, Malik AB, Tiruppathi C. Bair AM, et al. Among authors: thippegowda pb. J Biol Chem. 2009 Jan 2;284(1):563-574. doi: 10.1074/jbc.M803984200. Epub 2008 Nov 6. J Biol Chem. 2009. PMID: 18990707 Free PMC article.
The transcription factor DREAM represses the deubiquitinase A20 and mediates inflammation.
Tiruppathi C, Soni D, Wang DM, Xue J, Singh V, Thippegowda PB, Cheppudira BP, Mishra RK, Debroy A, Qian Z, Bachmaier K, Zhao YY, Christman JW, Vogel SM, Ma A, Malik AB. Tiruppathi C, et al. Among authors: thippegowda pb. Nat Immunol. 2014 Mar;15(3):239-47. doi: 10.1038/ni.2823. Epub 2014 Feb 2. Nat Immunol. 2014. PMID: 24487321 Free PMC article.
Corosolic Acid Inhibits Secretory Phospholipase A2IIa as an Anti-Inflammatory Function and Exhibits Anti-Tumor Activity in Ehrlich Ascites Carcinoma Bearing Mice.
Pundalik S, Hanumappa KR, Giresha AS, Urs D, Rajashekarappa S, Muniyappa N, Jamballi G M, Kuaramkote Shivanna D, S Meti R, Anekere Dasappa Setty S, Thippegowda PB, Krishnappa DK. Pundalik S, et al. Among authors: thippegowda pb. J Inflamm Res. 2022 Dec 31;15:6905-6921. doi: 10.2147/JIR.S383441. eCollection 2022. J Inflamm Res. 2022. PMID: 36619941 Free PMC article.