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B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models.
Proc Natl Acad Sci U S A. 2020 Sep 15;117(37):22920-22931. doi: 10.1073/pnas.2004489117. Epub 2020 Sep 1.
Proc Natl Acad Sci U S A. 2020.
PMID: 32873644
Free PMC article.
HIV-1 VACCINES. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen.
Jardine JG, Ota T, Sok D, Pauthner M, Kulp DW, Kalyuzhniy O, Skog PD, Thinnes TC, Bhullar D, Briney B, Menis S, Jones M, Kubitz M, Spencer S, Adachi Y, Burton DR, Schief WR, Nemazee D.
Jardine JG, et al. Among authors: thinnes tc.
Science. 2015 Jul 10;349(6244):156-61. doi: 10.1126/science.aac5894. Epub 2015 Jun 18.
Science. 2015.
PMID: 26089355
Free PMC article.
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Disease in the Pld4thss/thss Model of Murine Lupus Requires TLR9.
Gavin AL, Blane TR, Thinnes TC, Gerlt E, Marshak-Rothstein A, Huang D, Nemazee D.
Gavin AL, et al. Among authors: thinnes tc.
Immunohorizons. 2023 Aug 1;7(8):577-586. doi: 10.4049/immunohorizons.2300058.
Immunohorizons. 2023.
PMID: 37555846
Free PMC article.
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Cleavage of DNA and RNA by PLD3 and PLD4 limits autoinflammatory triggering by multiple sensors.
Gavin AL, Huang D, Blane TR, Thinnes TC, Murakami Y, Fukui R, Miyake K, Nemazee D.
Gavin AL, et al. Among authors: thinnes tc.
Nat Commun. 2021 Oct 7;12(1):5874. doi: 10.1038/s41467-021-26150-w.
Nat Commun. 2021.
PMID: 34620855
Free PMC article.
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PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing.
Gavin AL, Huang D, Huber C, Mårtensson A, Tardif V, Skog PD, Blane TR, Thinnes TC, Osborn K, Chong HS, Kargaran F, Kimm P, Zeitjian A, Sielski RL, Briggs M, Schulz SR, Zarpellon A, Cravatt B, Pang ES, Teijaro J, de la Torre JC, O'Keeffe M, Hochrein H, Damme M, Teyton L, Lawson BR, Nemazee D.
Gavin AL, et al. Among authors: thinnes tc.
Nat Immunol. 2018 Sep;19(9):942-953. doi: 10.1038/s41590-018-0179-y. Epub 2018 Aug 13.
Nat Immunol. 2018.
PMID: 30111894
Free PMC article.
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The Bacterial Peptidoglycan-Sensing Molecules NOD1 and NOD2 Promote CD8+ Thymocyte Selection.
Martinic MM, Caminschi I, O'Keeffe M, Thinnes TC, Grumont R, Gerondakis S, McKay DB, Nemazee D, Gavin AL.
Martinic MM, et al. Among authors: thinnes tc.
J Immunol. 2017 Apr 1;198(7):2649-2660. doi: 10.4049/jimmunol.1601462. Epub 2017 Feb 15.
J Immunol. 2017.
PMID: 28202617
Free PMC article.
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Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles.
He L, de Val N, Morris CD, Vora N, Thinnes TC, Kong L, Azadnia P, Sok D, Zhou B, Burton DR, Wilson IA, Nemazee D, Ward AB, Zhu J.
He L, et al. Among authors: thinnes tc.
Nat Commun. 2016 Jun 28;7:12041. doi: 10.1038/ncomms12041.
Nat Commun. 2016.
PMID: 27349934
Free PMC article.
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Plasminogen has a broad extrahepatic distribution.
Zhang L, Seiffert D, Fowler BJ, Jenkins GR, Thinnes TC, Loskutoff DJ, Parmer RJ, Miles LA.
Zhang L, et al. Among authors: thinnes tc.
Thromb Haemost. 2002 Mar;87(3):493-501.
Thromb Haemost. 2002.
PMID: 11916082
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