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Design of a series of bicyclic HIV-1 integrase inhibitors. Part 1: selection of the scaffold.
Bioorg Med Chem Lett. 2010 Oct 1;20(19):5913-7. doi: 10.1016/j.bmcl.2010.07.079. Epub 2010 Jul 27.
Bioorg Med Chem Lett. 2010.
PMID: 20727748
Design of a series of bicyclic HIV-1 integrase inhibitors. Part 2: azoles: effective metal chelators.
Le G, Vandegraaff N, Rhodes DI, Jones ED, Coates JA, Thienthong N, Winfield LJ, Lu L, Li X, Yu C, Feng X, Deadman JJ.
Le G, et al. Among authors: thienthong n.
Bioorg Med Chem Lett. 2010 Oct 1;20(19):5909-12. doi: 10.1016/j.bmcl.2010.07.081. Epub 2010 Jul 27.
Bioorg Med Chem Lett. 2010.
PMID: 20727753
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Structural basis for a new mechanism of inhibition of HIV-1 integrase identified by fragment screening and structure-based design.
Rhodes DI, Peat TS, Vandegraaff N, Jeevarajah D, Le G, Jones ED, Smith JA, Coates JA, Winfield LJ, Thienthong N, Newman J, Lucent D, Ryan JH, Savage GP, Francis CL, Deadman JJ.
Rhodes DI, et al. Among authors: thienthong n.
Antivir Chem Chemother. 2011 Mar 7;21(4):155-68. doi: 10.3851/IMP1716.
Antivir Chem Chemother. 2011.
PMID: 21602613
Free article.
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Small molecule inhibitors of the LEDGF site of human immunodeficiency virus integrase identified by fragment screening and structure based design.
Peat TS, Rhodes DI, Vandegraaff N, Le G, Smith JA, Clark LJ, Jones ED, Coates JA, Thienthong N, Newman J, Dolezal O, Mulder R, Ryan JH, Savage GP, Francis CL, Deadman JJ.
Peat TS, et al. Among authors: thienthong n.
PLoS One. 2012;7(7):e40147. doi: 10.1371/journal.pone.0040147. Epub 2012 Jul 10.
PLoS One. 2012.
PMID: 22808106
Free PMC article.
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Pulmonary administration of a doxorubicin-conjugated dendrimer enhances drug exposure to lung metastases and improves cancer therapy.
Kaminskas LM, McLeod VM, Ryan GM, Kelly BD, Haynes JM, Williamson M, Thienthong N, Owen DJ, Porter CJ.
Kaminskas LM, et al. Among authors: thienthong n.
J Control Release. 2014 Jun 10;183:18-26. doi: 10.1016/j.jconrel.2014.03.012. Epub 2014 Mar 14.
J Control Release. 2014.
PMID: 24637466
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