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PRMT5 inhibition disrupts splicing and stemness in glioblastoma.
Sachamitr P, Ho JC, Ciamponi FE, Ba-Alawi W, Coutinho FJ, Guilhamon P, Kushida MM, Cavalli FMG, Lee L, Rastegar N, Vu V, Sánchez-Osuna M, Coulombe-Huntington J, Kanshin E, Whetstone H, Durand M, Thibault P, Hart K, Mangos M, Veyhl J, Chen W, Tran N, Duong BC, Aman AM, Che X, Lan X, Whitley O, Zaslaver O, Barsyte-Lovejoy D, Richards LM, Restall I, Caudy A, Röst HL, Bonday ZQ, Bernstein M, Das S, Cusimano MD, Spears J, Bader GD, Pugh TJ, Tyers M, Lupien M, Haibe-Kains B, Artee Luchman H, Weiss S, Massirer KB, Prinos P, Arrowsmith CH, Dirks PB. Sachamitr P, et al. Among authors: thibault p. Nat Commun. 2021 Feb 12;12(1):979. doi: 10.1038/s41467-021-21204-5. Nat Commun. 2021. PMID: 33579912 Free PMC article.
Identification of alternative splicing markers for breast cancer.
Venables JP, Klinck R, Bramard A, Inkel L, Dufresne-Martin G, Koh C, Gervais-Bird J, Lapointe E, Froehlich U, Durand M, Gendron D, Brosseau JP, Thibault P, Lucier JF, Tremblay K, Prinos P, Wellinger RJ, Chabot B, Rancourt C, Elela SA. Venables JP, et al. Among authors: thibault p. Cancer Res. 2008 Nov 15;68(22):9525-31. doi: 10.1158/0008-5472.CAN-08-1769. Cancer Res. 2008. PMID: 19010929
Cancer-associated regulation of alternative splicing.
Venables JP, Klinck R, Koh C, Gervais-Bird J, Bramard A, Inkel L, Durand M, Couture S, Froehlich U, Lapointe E, Lucier JF, Thibault P, Rancourt C, Tremblay K, Prinos P, Chabot B, Elela SA. Venables JP, et al. Among authors: thibault p. Nat Struct Mol Biol. 2009 Jun;16(6):670-6. doi: 10.1038/nsmb.1608. Epub 2009 May 17. Nat Struct Mol Biol. 2009. PMID: 19448617
Alternative splicing of SYK regulates mitosis and cell survival.
Prinos P, Garneau D, Lucier JF, Gendron D, Couture S, Boivin M, Brosseau JP, Lapointe E, Thibault P, Durand M, Tremblay K, Gervais-Bird J, Nwilati H, Klinck R, Chabot B, Perreault JP, Wellinger RJ, Elela SA. Prinos P, et al. Among authors: thibault p. Nat Struct Mol Biol. 2011 Jun;18(6):673-9. doi: 10.1038/nsmb.2040. Epub 2011 May 8. Nat Struct Mol Biol. 2011. PMID: 21552259
Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators.
Michelle L, Cloutier A, Toutant J, Shkreta L, Thibault P, Durand M, Garneau D, Gendron D, Lapointe E, Couture S, Le Hir H, Klinck R, Elela SA, Prinos P, Chabot B. Michelle L, et al. Among authors: thibault p. Mol Cell Biol. 2012 Mar;32(5):954-67. doi: 10.1128/MCB.06130-11. Epub 2011 Dec 27. Mol Cell Biol. 2012. PMID: 22203037 Free PMC article.
Tumor microenvironment-associated modifications of alternative splicing.
Brosseau JP, Lucier JF, Nwilati H, Thibault P, Garneau D, Gendron D, Durand M, Couture S, Lapointe E, Prinos P, Klinck R, Perreault JP, Chabot B, Abou-Elela S. Brosseau JP, et al. Among authors: thibault p. RNA. 2014 Feb;20(2):189-201. doi: 10.1261/rna.042168.113. Epub 2013 Dec 11. RNA. 2014. PMID: 24335142 Free PMC article.
Global profiling of alternative RNA splicing events provides insights into molecular differences between various types of hepatocellular carcinoma.
Tremblay MP, Armero VE, Allaire A, Boudreault S, Martenon-Brodeur C, Durand M, Lapointe E, Thibault P, Tremblay-Létourneau M, Perreault JP, Scott MS, Bisaillon M. Tremblay MP, et al. Among authors: thibault p. BMC Genomics. 2016 Aug 26;17(1):683. doi: 10.1186/s12864-016-3029-z. BMC Genomics. 2016. PMID: 27565572 Free PMC article.
779 results