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Discovery and Functional Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody.
Van Kolen K, Malia TJ, Theunis C, Nanjunda R, Teplyakov A, Ernst R, Wu SJ, Luo J, Borgers M, Vandermeeren M, Bottelbergs A, Wintmolders C, Lacy E, Maurin H, Larsen P, Willems R, Van De Casteele T, Triana-Baltzer G, Slemmon R, Galpern W, Trojanowski JQ, Sun H, Mercken MH. Van Kolen K, et al. Among authors: theunis c. J Alzheimers Dis. 2020;77(4):1397-1416. doi: 10.3233/JAD-200544. J Alzheimers Dis. 2020. PMID: 32894244
Anti-Tau Monoclonal Antibodies Derived from Soluble and Filamentous Tau Show Diverse Functional Properties in vitro and in vivo.
Vandermeeren M, Borgers M, Van Kolen K, Theunis C, Vasconcelos B, Bottelbergs A, Wintmolders C, Daneels G, Willems R, Dockx K, Delbroek L, Marreiro A, Ver Donck L, Sousa C, Nanjunda R, Lacy E, Van De Casteele T, Van Dam D, De Deyn PP, Kemp JA, Malia TJ, Mercken MH. Vandermeeren M, et al. Among authors: theunis c. J Alzheimers Dis. 2018;65(1):265-281. doi: 10.3233/JAD-180404. J Alzheimers Dis. 2018. PMID: 30040731
Development of immunoprecipitation - two-dimensional liquid chromatography - mass spectrometry methodology as biomarker read-out to quantify phosphorylated tau in cerebrospinal fluid from Alzheimer disease patients.
Bijttebier S, Theunis C, Jahouh F, Martins DR, Verhemeldonck M, Grauwen K, Dillen L, Mercken M. Bijttebier S, et al. Among authors: theunis c. J Chromatogr A. 2021 Aug 16;1651:462299. doi: 10.1016/j.chroma.2021.462299. Epub 2021 May 28. J Chromatogr A. 2021. PMID: 34107398 Free article.
Cerebrospinal fluid p-tau217 performs better than p-tau181 as a biomarker of Alzheimer's disease.
Janelidze S, Stomrud E, Smith R, Palmqvist S, Mattsson N, Airey DC, Proctor NK, Chai X, Shcherbinin S, Sims JR, Triana-Baltzer G, Theunis C, Slemmon R, Mercken M, Kolb H, Dage JL, Hansson O. Janelidze S, et al. Among authors: theunis c. Nat Commun. 2020 Apr 3;11(1):1683. doi: 10.1038/s41467-020-15436-0. Nat Commun. 2020. PMID: 32246036 Free PMC article.
19 results