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Diabetes impairs cardioprotective function of endothelial progenitor cell-derived extracellular vesicles via H3K9Ac inhibition.
Huang G, Cheng Z, Hildebrand A, Wang C, Cimini M, Roy R, Lucchese AM, Benedict C, Mallaredy V, Magadum A, Joladarashi D, Thej C, Gonzalez C, Trungcao M, Garikipati VNS, Elrod JW, Koch WJ, Kishore R. Huang G, et al. Among authors: thej c. Theranostics. 2022 May 21;12(9):4415-4430. doi: 10.7150/thno.70821. eCollection 2022. Theranostics. 2022. PMID: 35673580 Free PMC article.
Administration of Adult Human Bone Marrow-Derived, Cultured, Pooled, Allogeneic Mesenchymal Stromal Cells in Critical Limb Ischemia Due to Buerger's Disease: Phase II Study Report Suggests Clinical Efficacy.
Gupta PK, Krishna M, Chullikana A, Desai S, Murugesan R, Dutta S, Sarkar U, Raju R, Dhar A, Parakh R, Jeyaseelan L, Viswanathan P, Vellotare PK, Seetharam RN, Thej C, Rengasamy M, Balasubramanian S, Majumdar AS. Gupta PK, et al. Among authors: thej c. Stem Cells Transl Med. 2017 Mar;6(3):689-699. doi: 10.5966/sctm.2016-0237. Epub 2016 Oct 5. Stem Cells Transl Med. 2017. PMID: 28297569 Free PMC article. Clinical Trial.
Phase IV postmarketing surveillance study shows continued efficacy and safety of Stempeucel in patients with critical limb ischemia due to Buerger's disease.
Gupta PK, Dutta S, Kala S, Nekkanti M, Desai SC, Mahapatra SS, Dhar A, Raju R, M R, Behera A, P S, Raviraja NS, Viswanathan P, Chandrashekar M, Thej C, K V P, Abraham J, Boggarapu H, Udaykumar K. Gupta PK, et al. Among authors: thej c. Stem Cells Transl Med. 2021 Dec;10(12):1602-1613. doi: 10.1002/sctm.21-0197. Epub 2021 Sep 13. Stem Cells Transl Med. 2021. PMID: 34519179 Free PMC article. Clinical Trial.
Efficacy and safety of adult human bone marrow-derived, cultured, pooled, allogeneic mesenchymal stromal cells (Stempeucel®): preclinical and clinical trial in osteoarthritis of the knee joint.
Gupta PK, Chullikana A, Rengasamy M, Shetty N, Pandey V, Agarwal V, Wagh SY, Vellotare PK, Damodaran D, Viswanathan P, Thej C, Balasubramanian S, Majumdar AS. Gupta PK, et al. Among authors: thej c. Arthritis Res Ther. 2016 Dec 20;18(1):301. doi: 10.1186/s13075-016-1195-7. Arthritis Res Ther. 2016. PMID: 27993154 Free PMC article. Clinical Trial.
Human bone marrow-derived, pooled, allogeneic mesenchymal stromal cells manufactured from multiple donors at different times show comparable biological functions in vitro, and in vivo to repair limb ischemia.
Thej C, Balasubramanian S, Rengasamy M, Walvekar A, Swamynathan P, Raj SS, Shahani P, Siddikuzzaman, Kolkundkar U, Seetharam RN, Gupta PK, Majumdar AS. Thej C, et al. Stem Cell Res Ther. 2021 May 10;12(1):279. doi: 10.1186/s13287-021-02330-9. Stem Cell Res Ther. 2021. PMID: 33971964 Free PMC article.
Transplantation of human bone marrow mesenchymal stromal cells reduces liver fibrosis more effectively than Wharton's jelly mesenchymal stromal cells.
Rengasamy M, Singh G, Fakharuzi NA, Siddikuzzaman, Balasubramanian S, Swamynathan P, Thej C, Sasidharan G, Gupta PK, Das AK, Rahman AZA, Fakiruddin KS, Nian LM, Zakaria Z, Majumdar AS. Rengasamy M, et al. Among authors: thej c. Stem Cell Res Ther. 2017 Jun 13;8(1):143. doi: 10.1186/s13287-017-0595-1. Stem Cell Res Ther. 2017. PMID: 28610623 Free PMC article.
14 results