Theisen ER - Search Results

1

Therapeutic Targeting of KDM1A/LSD1 in Ewing Sarcoma with SP-2509 Engages the Endoplasmic Reticulum Stress Response.

Pishas KI, Drenberg CD, Taslim C, Theisen ER, Johnson KM, Saund RS, Pop IL, Crompton BD, Lawlor ER, Tirode F, Mora J, Delattre O, Beckerle MC, Callen DF, Sharma S, Lessnick SL. Pishas KI, et al. Among authors: theisen er. Mol Cancer Ther. 2018 Sep;17(9):1902-1916. doi: 10.1158/1535-7163.MCT-18-0373. Epub 2018 Jul 11. Mol Cancer Ther. 2018. PMID: 29997151 Free PMC article.

2

High-throughput virtual screening identifies novel N'-(1-phenylethylidene)-benzohydrazides as potent, specific, and reversible LSD1 inhibitors.

Sorna V, Theisen ER, Stephens B, Warner SL, Bearss DJ, Vankayalapati H, Sharma S. Sorna V, et al. Among authors: theisen er. J Med Chem. 2013 Dec 12;56(23):9496-508. doi: 10.1021/jm400870h. Epub 2013 Nov 23. J Med Chem. 2013. PMID: 24237195

3

Reversible LSD1 inhibition interferes with global EWS/ETS transcriptional activity and impedes Ewing sarcoma tumor growth.

Sankar S, Theisen ER, Bearss J, Mulvihill T, Hoffman LM, Sorna V, Beckerle MC, Sharma S, Lessnick SL. Sankar S, et al. Among authors: theisen er. Clin Cancer Res. 2014 Sep 1;20(17):4584-97. doi: 10.1158/1078-0432.CCR-14-0072. Epub 2014 Jun 24. Clin Cancer Res. 2014. PMID: 24963049 Free PMC article.

4

Reversible inhibition of lysine specific demethylase 1 is a novel anti-tumor strategy for poorly differentiated endometrial carcinoma.

Theisen ER, Gajiwala S, Bearss J, Sorna V, Sharma S, Janat-Amsbury M. Theisen ER, et al. BMC Cancer. 2014 Oct 9;14:752. doi: 10.1186/1471-2407-14-752. BMC Cancer. 2014. PMID: 25300887 Free PMC article.

5

Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting.

Theisen ER, Pishas KI, Saund RS, Lessnick SL. Theisen ER, et al. Oncotarget. 2016 Apr 5;7(14):17616-30. doi: 10.18632/oncotarget.7124. Oncotarget. 2016. PMID: 26848860 Free PMC article. Review.

6

Role for the EWS domain of EWS/FLI in binding GGAA-microsatellites required for Ewing sarcoma anchorage independent growth.

Johnson KM, Mahler NR, Saund RS, Theisen ER, Taslim C, Callender NW, Crow JC, Miller KR, Lessnick SL. Johnson KM, et al. Among authors: theisen er. Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):9870-9875. doi: 10.1073/pnas.1701872114. Epub 2017 Aug 28. Proc Natl Acad Sci U S A. 2017. PMID: 28847958 Free PMC article.

7

Transcriptomic analysis functionally maps the intrinsically disordered domain of EWS/FLI and reveals novel transcriptional dependencies for oncogenesis.

Theisen ER, Miller KR, Showpnil IA, Taslim C, Pishas KI, Lessnick SL. Theisen ER, et al. Genes Cancer. 2019 Feb;10(1-2):21-38. doi: 10.18632/genesandcancer.188. Genes Cancer. 2019. PMID: 30899417 Free PMC article.

8

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma.

Patel PO, Pishas KI, Taslim C, Selich-Anderson J, Theisen ER, Lessnick SL. Patel PO, et al. Among authors: theisen er. Oncotarget. 2019 Jun 11;10(39):3865-3878. doi: 10.18632/oncotarget.26988. eCollection 2019 Jun 11. Oncotarget. 2019. PMID: 31231465 Free PMC article.

9

Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis.

Showpnil IA, Miller KR, Taslim C, Pishas KI, Lessnick SL, Theisen ER. Showpnil IA, et al. Among authors: theisen er. J Vis Exp. 2020 Jun 27;(160):10.3791/61564. doi: 10.3791/61564. J Vis Exp. 2020. PMID: 32658189 Free PMC article.

10

Chromatin profiling reveals relocalization of lysine-specific demethylase 1 by an oncogenic fusion protein.

Theisen ER, Selich-Anderson J, Miller KR, Tanner JM, Taslim C, Pishas KI, Sharma S, Lessnick SL. Theisen ER, et al. Epigenetics. 2021 Apr;16(4):405-424. doi: 10.1080/15592294.2020.1805678. Epub 2020 Aug 25. Epigenetics. 2021. PMID: 32842875 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

16 results

Search Page