De novo production of bioactive sesterterpenoid ophiobolins in Saccharomyces cerevisiae cell factories.
Zhang C, Wu J, Sun Q, Ding S, Tao H, He Y, Qiu H, Shu B, Zhu D, Zhu H, Hong K.
Zhang C, et al.
Microb Cell Fact. 2024 May 6;23(1):129. doi: 10.1186/s12934-024-02406-0.
Microb Cell Fact. 2024.
PMID: 38711040
The whole-cell biotransformation methods were further combined with metabolic engineering to enhance the expression of key ophiobolin biosynthetic genes and improve the supply of precursors and cofactors. ...
The whole-cell biotransformation methods were further combined with metabolic engineering to enhance the expression of key ophiobolin …