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The conducting state of TRPA1 modulates channel lateral mobility.
Cell Calcium. 2023 Dec;116:102800. doi: 10.1016/j.ceca.2023.102800. Epub 2023 Sep 18.
Cell Calcium. 2023.
PMID: 37776645
TRPswitch-A Step-Function Chemo-optogenetic Ligand for the Vertebrate TRPA1 Channel.
Lam PY, Thawani AR, Balderas E, White AJP, Chaudhuri D, Fuchter MJ, Peterson RT.
Lam PY, et al. Among authors: thawani ar.
J Am Chem Soc. 2020 Oct 14;142(41):17457-17468. doi: 10.1021/jacs.0c06811. Epub 2020 Oct 5.
J Am Chem Soc. 2020.
PMID: 32966062
Free PMC article.
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A combinatorial approach to improving the performance of azoarene photoswitches.
Calbo J, Thawani AR, Gibson RSL, White AJP, Fuchter MJ.
Calbo J, et al. Among authors: thawani ar.
Beilstein J Org Chem. 2019 Nov 14;15:2753-2764. doi: 10.3762/bjoc.15.266. eCollection 2019.
Beilstein J Org Chem. 2019.
PMID: 31807208
Free PMC article.
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[5]-Helistatins: Tubulin-Binding Helicenes with Antimitotic Activity.
Rushworth JL, Thawani AR, Fajardo-Ruiz E, Meiring JCM, Heise C, White AJP, Akhmanova A, Brandt JR, Thorn-Seshold O, Fuchter MJ.
Rushworth JL, et al. Among authors: thawani ar.
JACS Au. 2022 Oct 19;2(11):2561-2570. doi: 10.1021/jacsau.2c00435. eCollection 2022 Nov 28.
JACS Au. 2022.
PMID: 36465552
Free PMC article.
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Data-driven discovery of molecular photoswitches with multioutput Gaussian processes.
Griffiths RR, Greenfield JL, Thawani AR, Jamasb AR, Moss HB, Bourached A, Jones P, McCorkindale W, Aldrick AA, Fuchter MJ, Lee AA.
Griffiths RR, et al. Among authors: thawani ar.
Chem Sci. 2022 Nov 10;13(45):13541-13551. doi: 10.1039/d2sc04306h. eCollection 2022 Nov 23.
Chem Sci. 2022.
PMID: 36507171
Free PMC article.
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Activity-based protein profiling reveals deubiquitinase and aldehyde dehydrogenase targets of a cyanopyrrolidine probe.
Panyain N, Godinat A, Thawani AR, Lachiondo-Ortega S, Mason K, Elkhalifa S, Smith LM, Harrigan JA, Tate EW.
Panyain N, et al. Among authors: thawani ar.
RSC Med Chem. 2021 Aug 16;12(11):1935-1943. doi: 10.1039/d1md00218j. eCollection 2021 Nov 17.
RSC Med Chem. 2021.
PMID: 34820624
Free PMC article.
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Optimization of a Series of RIPK2 PROTACs.
Miah AH, Smith IED, Rackham M, Mares A, Thawani AR, Nagilla R, Haile PA, Votta BJ, Gordon LJ, Watt G, Denyer J, Fisher DT, Dace P, Giffen P, Goncalves A, Churcher I, Scott-Stevens P, Harling JD.
Miah AH, et al. Among authors: thawani ar.
J Med Chem. 2021 Sep 9;64(17):12978-13003. doi: 10.1021/acs.jmedchem.1c01118. Epub 2021 Aug 25.
J Med Chem. 2021.
PMID: 34432979
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Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2.
Mares A, Miah AH, Smith IED, Rackham M, Thawani AR, Cryan J, Haile PA, Votta BJ, Beal AM, Capriotti C, Reilly MA, Fisher DT, Zinn N, Bantscheff M, MacDonald TT, Vossenkamper A, Dace P, Churcher I, Benowitz AB, Watt G, Denyer J, Scott-Stevens P, Harling JD.
Mares A, et al. Among authors: thawani ar.
Commun Biol. 2020 Mar 20;3(1):140. doi: 10.1038/s42003-020-0868-6.
Commun Biol. 2020.
PMID: 32198438
Free PMC article.
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