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Pro-cachectic factors link experimental and human chronic kidney disease to skeletal muscle wasting programs.
Solagna F, Tezze C, Lindenmeyer MT, Lu S, Wu G, Liu S, Zhao Y, Mitchell R, Meyer C, Omairi S, Kilic T, Paolini A, Ritvos O, Pasternack A, Matsakas A, Kylies D, Wiesch JSZ, Turner JE, Wanner N, Nair V, Eichinger F, Menon R, Martin IV, Klinkhammer BM, Hoxha E, Cohen CD, Tharaux PL, Boor P, Ostendorf T, Kretzler M, Sandri M, Kretz O, Puelles VG, Patel K, Huber TB. Solagna F, et al. Among authors: tharaux pl. J Clin Invest. 2021 Jun 1;131(11):e135821. doi: 10.1172/JCI135821. J Clin Invest. 2021. PMID: 34060483 Free PMC article.
How many ways can a podocyte die?
Tharaux PL, Huber TB. Tharaux PL, et al. Semin Nephrol. 2012 Jul;32(4):394-404. doi: 10.1016/j.semnephrol.2012.06.011. Semin Nephrol. 2012. PMID: 22958494 Free article. Review.
Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1.
Lee HW, Khan SQ, Khaliqdina S, Altintas MM, Grahammer F, Zhao JL, Koh KH, Tardi NJ, Faridi MH, Geraghty T, Cimbaluk DJ, Susztak K, Moita LF, Baltimore D, Tharaux PL, Huber TB, Kretzler M, Bitzer M, Reiser J, Gupta V. Lee HW, et al. Among authors: tharaux pl. J Biol Chem. 2017 Jan 13;292(2):732-747. doi: 10.1074/jbc.M116.753822. Epub 2016 Dec 2. J Biol Chem. 2017. PMID: 27913625 Free PMC article.
Targeting mTOR Signaling Can Prevent the Progression of FSGS.
Zschiedrich S, Bork T, Liang W, Wanner N, Eulenbruch K, Munder S, Hartleben B, Kretz O, Gerber S, Simons M, Viau A, Burtin M, Wei C, Reiser J, Herbach N, Rastaldi MP, Cohen CD, Tharaux PL, Terzi F, Walz G, Gödel M, Huber TB. Zschiedrich S, et al. Among authors: tharaux pl. J Am Soc Nephrol. 2017 Jul;28(7):2144-2157. doi: 10.1681/ASN.2016050519. Epub 2017 Mar 7. J Am Soc Nephrol. 2017. PMID: 28270414 Free PMC article.
Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis.
Henique C, Bollée G, Loyer X, Grahammer F, Dhaun N, Camus M, Vernerey J, Guyonnet L, Gaillard F, Lazareth H, Meyer C, Bensaada I, Legrès L, Satoh T, Akira S, Bruneval P, Dimmeler S, Tedgui A, Karras A, Thervet E, Nochy D, Huber TB, Mesnard L, Lenoir O, Tharaux PL. Henique C, et al. Among authors: tharaux pl. Nat Commun. 2017 Nov 28;8(1):1829. doi: 10.1038/s41467-017-01885-7. Nat Commun. 2017. PMID: 29184126 Free PMC article.
The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression.
Lazareth H, Henique C, Lenoir O, Puelles VG, Flamant M, Bollée G, Fligny C, Camus M, Guyonnet L, Millien C, Gaillard F, Chipont A, Robin B, Fabrega S, Dhaun N, Camerer E, Kretz O, Grahammer F, Braun F, Huber TB, Nochy D, Mandet C, Bruneval P, Mesnard L, Thervet E, Karras A, Le Naour F, Rubinstein E, Boucheix C, Alexandrou A, Moeller MJ, Bouzigues C, Tharaux PL. Lazareth H, et al. Among authors: tharaux pl. Nat Commun. 2019 Jul 24;10(1):3303. doi: 10.1038/s41467-019-11013-2. Nat Commun. 2019. PMID: 31341160 Free PMC article.
Podocytes maintain high basal levels of autophagy independent of mtor signaling.
Bork T, Liang W, Yamahara K, Lee P, Tian Z, Liu S, Schell C, Thedieck K, Hartleben B, Patel K, Tharaux PL, Lenoir O, Huber TB. Bork T, et al. Among authors: tharaux pl. Autophagy. 2020 Nov;16(11):1932-1948. doi: 10.1080/15548627.2019.1705007. Epub 2019 Dec 23. Autophagy. 2020. PMID: 31865844 Free PMC article.
162 results